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Tmem65 Gene Detail
Summary
  • Symbol
    Tmem65
  • Name
    transmembrane protein 65
  • Synonyms
    2610029O13Rik, 4930438D12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922118
    NCBI Gene: 74868
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:58782269-58823638 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 25.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    301 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922118
protein coding gene Chr15:58782269-58823661 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021875
protein coding gene Chr15:57985813-58027129 (-)
A/J MGP_AJ_G0021835
protein coding gene Chr15:55717981-55759495 (-)
AKR/J MGP_AKRJ_G0021816
protein coding gene Chr15:57254332-57295596 (-)
BALB/cJ MGP_BALBcJ_G0021842
protein coding gene Chr15:55937520-55978866 (-)
C3H/HeJ MGP_C3HHeJ_G0021616
protein coding gene Chr15:57380203-57423209 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022281
protein coding gene Chr15:60234150-60277545 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019818
protein coding gene Chr15:52804875-52846838 (-)
CAST/EiJ MGP_CASTEiJ_G0021133
protein coding gene Chr15:58035274-58079015 (-)
CBA/J MGP_CBAJ_G0021585
protein coding gene Chr15:62318239-62359350 (-)
DBA/2J MGP_DBA2J_G0021709
protein coding gene Chr15:55631415-55673124 (-)
FVB/NJ MGP_FVBNJ_G0021687
protein coding gene Chr15:54677154-54719572 (-)
LP/J MGP_LPJ_G0021779
protein coding gene Chr15:57841494-57882796 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021711
protein coding gene Chr15:67385373-67429613 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022304
protein coding gene Chr15:57661193-57704047 (-)
PWK/PhJ MGP_PWKPhJ_G0020878
protein coding gene Chr15:55630250-55673024 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020715
protein coding gene Chr15:57458424-57503378 (-)
WSB/EiJ MGP_WSBEiJ_G0021188
protein coding gene Chr15:57658866-57700840 (-)



Homology
more
  • Human Ortholog
    TMEM65, transmembrane protein 65
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM65, transmembrane protein 65
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 157378
    neXtProt AC: NX_Q6PI78
    UniProt: Q6PI78

  • Chr Location
    8q24.13; chr8:124306189-124372699 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 45494
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TMEM65
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    1
  • Gene trapped
    3
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    5 involving Tmem65
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062373 Ensembl Gene Model | MGI Sequence Detail 41370 C57BL/6J ±  kb
transcript ENSMUST00000072113 Ensembl | MGI Sequence Detail 3747 Not Applicable  
polypeptide ENSMUSP00000071984 Ensembl | MGI Sequence Detail 234 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 60
    cDNA 60

    Microarray probesets 6
Other
Accession IDs
less
MGI:1913702
References
more
  • Summaries
    All 51
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 4
    Phenotypes 27
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory