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Tmem65 Gene Detail
Summary
  • Symbol
    Tmem65
  • Name
    transmembrane protein 65
  • Synonyms
    2610029O13Rik, 4930438D12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922118
    NCBI Gene: 74868
Location & Maps
more
  • Sequence Map
    Chr15:58782269-58823530 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      41262 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 25.09 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TMEM65, transmembrane protein 65
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM65, transmembrane protein 65
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 157378
    neXtProt AC: NX_Q6PI78

  • Chr Location
    8q24.13; chr8:124306189-124372699 (-)  GRCh38.p2

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    3
  • Gene trapped
    3
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    5 involving Tmem65
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020984 VEGA Gene Model | MGI Sequence Detail 41262 C57BL/6J ±  kb
transcript OTTMUST00000049620 VEGA | MGI Sequence Detail 3747 Not Applicable  
polypeptide OTTMUSP00000023023 VEGA | MGI Sequence Detail 234 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    301 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000029815 transmembrane protein 65
  • InterPro Domains
    IPR019537 Transmembrane protein 65
Molecular
Reagents
less
  • All nucleic 58
    cDNA 58

    Microarray probesets 6
Other
Accession IDs
less
MGI:1913702
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 4
    Phenotypes 26
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:227218 Sharma P, et al., Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nat Commun. 2015;6:8391

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory