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Ppa2 Gene Detail
Summary
  • Symbol
    Ppa2
  • Name
    pyrophosphatase (inorganic) 2
  • Synonyms
    1110013G13Rik, Sid6306
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922026
    NCBI Gene: 74776
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:133310110-133378235 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 61.71 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    203 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922026
 protein coding gene Chr3:133310070-133378235 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027898
 protein coding gene Chr3:136098793-136171568 (+)
A/J MGP_AJ_G0027856
 protein coding gene Chr3:131301179-131370565 (+)
AKR/J MGP_AKRJ_G0027821
 protein coding gene Chr3:134723849-134800245 (+)
BALB/cJ MGP_BALBcJ_G0027869
 protein coding gene Chr3:131146245-131218897 (+)
C3H/HeJ MGP_C3HHeJ_G0027598
 protein coding gene Chr3:135109050-135184607 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028312
 protein coding gene Chr3:140854034-140919515 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025650
 protein coding gene Chr3:126726521-126800672 (+)
CAST/EiJ MGP_CASTEiJ_G0027054
 protein coding gene Chr3:134880993-134982963 (+)
CBA/J MGP_CBAJ_G0027574
 protein coding gene Chr3:145635468-145706588 (+)
DBA/2J MGP_DBA2J_G0027714
 protein coding gene Chr3:130465231-130532998 (+)
FVB/NJ MGP_FVBNJ_G0027681
 protein coding gene Chr3:128056471-128124582 (+)
LP/J MGP_LPJ_G0027824
 protein coding gene Chr3:137579977-137653173 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027712
 protein coding gene Chr3:153628421-153698277 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028370
 protein coding gene Chr3:134380873-134449335 (+)
PWK/PhJ MGP_PWKPhJ_G0026778
 protein coding gene Chr3:130229618-130330137 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026603
 protein coding gene Chr3:132443157-132544987 (+)
WSB/EiJ MGP_WSBEiJ_G0027133
 protein coding gene Chr3:135148542-135217966 (+)



Homology
more
  • Human Ortholog
    PPA2, inorganic pyrophosphatase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PPA2, inorganic pyrophosphatase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSPC124, SCFAI, SCFI, SID6-306
  • Links
    NCBI Gene ID: 27068
    neXtProt AC: NX_Q9H2U2
    UniProt: Q9H2U2

  • Chr Location
    4q24; chr4:105369077-105474070 (-)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    94
  • Tissues
    94
  • cDNA Data
    69
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028013 Ensembl Gene Model | MGI Sequence Detail 68126 C57BL/6J ±  kb
transcript ENSMUST00000029644 Ensembl | MGI Sequence Detail 1226 Not Applicable  
polypeptide ENSMUSP00000029644 Ensembl | MGI Sequence Detail 330 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 69
    cDNA 69

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/10/2019
MGI 6.14 		The Jackson Laboratory