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Rita1 Gene Detail
Summary
  • Symbol
    Rita1
  • Name
    RBPJ interacting and tubulin associated 1
  • Synonyms
    1110008J03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922021
    NCBI Gene: 100764
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:120609058-120612589 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 60.63 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922021
protein coding gene Chr5:120594305-120612589 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030008
protein coding gene Chr5:123978943-123997534 (-)
A/J MGP_AJ_G0029972
protein coding gene Chr5:118840014-118858272 (-)
AKR/J MGP_AKRJ_G0029911
protein coding gene Chr5:122675549-122695978 (-)
BALB/cJ MGP_BALBcJ_G0029983
protein coding gene Chr5:120257554-120275798 (-)
C3H/HeJ MGP_C3HHeJ_G0029703
protein coding gene Chr5:123211710-123229647 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030438
protein coding gene Chr5:128632680-128652406 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027664
protein coding gene Chr5:113549936-113568547 (-)
CAST/EiJ MGP_CASTEiJ_G0029112
protein coding gene Chr5:122337156-122357264 (-)
CBA/J MGP_CBAJ_G0029671
protein coding gene Chr5:133624963-133645794 (-)
DBA/2J MGP_DBA2J_G0029821
protein coding gene Chr5:118925793-118944309 (-)
FVB/NJ MGP_FVBNJ_G0029777
protein coding gene Chr5:117851748-117871008 (-)
LP/J MGP_LPJ_G0029909
protein coding gene Chr5:124428329-124454719 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029808
protein coding gene Chr5:137588598-137610595 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030479
protein coding gene Chr5:122254342-122273997 (-)
PWK/PhJ MGP_PWKPhJ_G0028825
protein coding gene Chr5:117686507-117705472 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028664
protein coding gene Chr5:119914997-119936477 (-)
WSB/EiJ MGP_WSBEiJ_G0029187
protein coding gene Chr5:122847171-122867279 (-)



Homology
more
  • Human Ortholog
    RITA1, RBPJ interacting and tubulin associated 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RITA1, RBPJ interacting and tubulin associated 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C12orf52, RITA
  • Links
    NCBI Gene ID: 84934
    neXtProt AC: NX_Q96K30
    UniProt: Q96K30

  • Chr Location
    12q24.13; chr12:113185526-113192368 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100764 NCBI Gene Model | MGI Sequence Detail 3532 C57BL/6J ±  kb
transcript NM_133908 RefSeq | MGI Sequence Detail 1668 C57BL/6  
polypeptide Q9D1H0 UniProt | EBI | MGI Sequence Detail 253 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR031418 RBPJ-interacting and tubulin-associated protein 1
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140999, MGI:2141332
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:247196 Tabaja N, et al., Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes. J Biol Chem. 2017 Jun 23;292(25):10549-10563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory