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Hhatl Gene Detail
Summary
  • Symbol
    Hhatl
  • Name
    hedgehog acyltransferase-like
  • Synonyms
    1110011D13Rik, Gup1, Mg56, Mitsugumin 56
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922020
    NCBI Gene: 74770
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:121784016-121792507 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 72.62 cM, cytoband F4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    29 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922020
protein coding gene Chr9:121784016-121792507 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035450
protein coding gene Chr9:124744395-124752919 (-)
A/J MGP_AJ_G0035431
protein coding gene Chr9:119990067-119998556 (-)
AKR/J MGP_AKRJ_G0035364
protein coding gene Chr9:123188485-123196964 (-)
BALB/cJ MGP_BALBcJ_G0035427
protein coding gene Chr9:119898407-119907256 (-)
C3H/HeJ MGP_C3HHeJ_G0035134
protein coding gene Chr9:123647473-123656994 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035950
protein coding gene Chr9:128158136-128168953 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032832
protein coding gene Chr9:117153068-117161227 (-)
CAST/EiJ MGP_CASTEiJ_G0034439
protein coding gene Chr9:123682403-123692802 (-)
CBA/J MGP_CBAJ_G0035102
protein coding gene Chr9:132846577-132855056 (-)
DBA/2J MGP_DBA2J_G0035261
protein coding gene Chr9:119433247-119442041 (-)
FVB/NJ MGP_FVBNJ_G0035208
protein coding gene Chr9:118352331-118361108 (-)
LP/J MGP_LPJ_G0035340
protein coding gene Chr9:125082515-125091009 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035249
protein coding gene Chr9:133788513-133798430 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035969
protein coding gene Chr9:123630558-123639064 (-)
PWK/PhJ MGP_PWKPhJ_G0034143
protein coding gene Chr9:119893352-119902217 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033980
protein coding gene Chr9:123750972-123759385 (-)
WSB/EiJ MGP_WSBEiJ_G0034559
protein coding gene Chr9:123480607-123489457 (-)



Homology
more
  • Human Ortholog
    HHATL, hedgehog acyltransferase like
  • Vertebrate Orthologs
    10
  • Human Ortholog
    HHATL, hedgehog acyltransferase like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C3orf3, GUP1, MBOAT3, MSTP002, OACT3
  • Links
    NCBI Gene ID: 57467
    neXtProt AC: NX_Q9HCP6
    UniProt: Q9HCP6

  • Chr Location
    3p22.1; chr3:42692663-42702849 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 19287
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: HHATL
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74770 NCBI Gene Model | MGI Sequence Detail 8492 C57BL/6J ±  kb
    transcript NM_029095 RefSeq | MGI Sequence Detail 1870 C57BL/6  
    polypeptide Q9D1G3 UniProt | EBI | MGI Sequence Detail 503 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000008539 protein-cysteine N-palmitoyltransferase HHAT-like protein
    • InterPro Domains
      IPR004299 Membrane bound O-acyl transferase, MBOAT
      IPR032980 Protein-cysteine N-palmitoyltransferase HHAT-like protein
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 11

      Microarray probesets 4
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 3
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:220810 Van B, et al., Mitsugumin 56 (hedgehog acyltransferase-like) is a sarcoplasmic reticulum-resident protein essential for postnatal muscle maturation. FEBS Lett. 2015 Apr 28;589(10):1095-104

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    Funding Information
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    last database update
    02/23/2021
    MGI 6.16
    The Jackson Laboratory