About   Help   FAQ
Cnep1r1 Gene Detail
Summary
  • Symbol
    Cnep1r1
  • Name
    CTD nuclear envelope phosphatase 1 regulatory subunit 1
  • Synonyms
    5033428A16Rik, Tmem188
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921981
    NCBI Gene: 382030
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:88118769-88135110 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 43.06 cM, cytoband C4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    143 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921981
protein coding gene Chr8:88118735-88135197 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033915
protein coding gene Chr8:89172336-89193557 (+)
A/J MGP_AJ_G0033898
protein coding gene Chr8:85673060-85690617 (+)
AKR/J MGP_AKRJ_G0033824
protein coding gene Chr8:88183562-88200111 (+)
BALB/cJ MGP_BALBcJ_G0033891
protein coding gene Chr8:85835222-85851762 (+)
C3H/HeJ MGP_C3HHeJ_G0033601
protein coding gene Chr8:88800574-88818795 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034411
protein coding gene Chr8:92538570-92556839 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031353
protein coding gene Chr8:79658158-79673605 (+)
CAST/EiJ MGP_CASTEiJ_G0032932
protein coding gene Chr8:88218520-88235738 (+)
CBA/J MGP_CBAJ_G0033577
protein coding gene Chr8:95678534-95696982 (+)
DBA/2J MGP_DBA2J_G0033730
protein coding gene Chr8:85262952-85279408 (+)
FVB/NJ MGP_FVBNJ_G0033677
protein coding gene Chr8:84220944-84237803 (+)
LP/J MGP_LPJ_G0033822
protein coding gene Chr8:89290038-89306348 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033720
protein coding gene Chr8:98154981-98172483 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034430
protein coding gene Chr8:88189433-88206870 (+)
PWK/PhJ MGP_PWKPhJ_G0032635
protein coding gene Chr8:84533649-84550679 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032471
protein coding gene Chr8:87005635-87022955 (+)
WSB/EiJ MGP_WSBEiJ_G0033043
protein coding gene Chr8:88640258-88656552 (+)



Homology
more
  • Human Ortholog
    CNEP1R1, CTD nuclear envelope phosphatase 1 regulatory subunit 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CNEP1R1, CTD nuclear envelope phosphatase 1 regulatory subunit 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C16orf69, NEP1R1, NEP1-R1, TMEM188, TMP125
  • Links
    NCBI Gene ID: 255919
    neXtProt AC: NX_Q8N9A8
    UniProt: Q8N9A8

  • Chr Location
    16q12.1; chr16:50025206-50037088 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    31 phenotype references
  • All Mutations and Alleles
    10
  • Endonuclease-mediated
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Cnep1r1
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036810 Ensembl Gene Model | MGI Sequence Detail 16342 C57BL/6J ±  kb
transcript ENSMUST00000095214 Ensembl | MGI Sequence Detail 1731 Not Applicable  
polypeptide ENSMUSP00000092839 Ensembl | MGI Sequence Detail 125 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032629 nuclear envelope phosphatase-regulatory subunit 1
  • InterPro Domains
    IPR019168 Nuclear envelope phosphatase-regulatory subunit 1
Molecular
Reagents
less
  • All nucleic 83
    cDNA 83

    Microarray probesets 4
References
more
  • Summaries
    All 56
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 31
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54:113-145
  • Latest
    J:266142 Grosjean F, et al., Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice. PLoS One. 2018;13(9):e0204366

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/19/2019
MGI 6.13
The Jackson Laboratory