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Tmem114 Gene Detail
Summary
  • Symbol
    Tmem114
  • Name
    transmembrane protein 114
  • Synonyms
    4930511J11Rik, Cldn26
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921970
    NCBI Gene: 74720
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:8409276-8425136 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 3.84 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    54 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921970
protein coding gene Chr16:8409275-8425136 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022491
protein coding gene Chr16:5063552-5079216 (-)
A/J MGP_AJ_G0022453
protein coding gene Chr16:4758142-4776716 (-)
AKR/J MGP_AKRJ_G0022430
protein coding gene Chr16:5019323-5034999 (-)
BALB/cJ MGP_BALBcJ_G0022458
protein coding gene Chr16:4923250-4946821 (-)
C3H/HeJ MGP_C3HHeJ_G0022225
protein coding gene Chr16:5063490-5083441 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022907
protein coding gene Chr16:5198927-5216548 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020428
protein coding gene Chr16:4972132-4985002 (-)
CAST/EiJ MGP_CASTEiJ_G0021751
protein coding gene Chr16:5083073-5117767 (-)
CBA/J MGP_CBAJ_G0022194
protein coding gene Chr16:5402587-5425060 (-)
DBA/2J MGP_DBA2J_G0022325
protein coding gene Chr16:4809483-4825087 (-)
FVB/NJ MGP_FVBNJ_G0022300
protein coding gene Chr16:4797332-4814173 (-)
LP/J MGP_LPJ_G0022393
protein coding gene Chr16:5042827-5064574 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022322
protein coding gene Chr16:5194548-5213576 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022919
protein coding gene Chr16:4985564-5001831 (-)
PWK/PhJ MGP_PWKPhJ_G0021491
protein coding gene Chr16:4966199-5002020 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021322
protein coding gene Chr16:5043893-5063846 (-)
WSB/EiJ MGP_WSBEiJ_G0021800
protein coding gene Chr16:5027336-5046250 (-)



Homology
more
  • Human Ortholog
    TMEM114, transmembrane protein 114
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM114, transmembrane protein 114
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 283953
    neXtProt AC: NX_B3SHH9
    UniProt: B3SHH9

  • Chr Location
    16p13.2; chr16:8526549-8590193 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74720 NCBI Gene Model | MGI Sequence Detail 15861 C57BL/6J ±  kb
    transcript NM_029070 RefSeq | MGI Sequence Detail 1406 C57BL/6  
    polypeptide Q9D563 UniProt | EBI | MGI Sequence Detail 222 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      Genomic 1
      cDNA 5
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 26
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 4
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    05/14/2019
    MGI 6.14
    The Jackson Laboratory