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Tdrd9 Gene Detail
Summary
  • Symbol
    Tdrd9
  • Name
    tudor domain containing 9
  • Synonyms
    4930441E05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921941
    NCBI Gene: 74691
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:111971559-112068854 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 61.14 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1176 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921941
protein coding gene Chr12:111971469-112068854 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020146
protein coding gene Chr12:114408217-114500975 (+)
A/J MGP_AJ_G0020102
protein coding gene Chr12:110002791-110090241 (+)
AKR/J MGP_AKRJ_G0020077
protein coding gene Chr12:113169629-113266391 (+)
BALB/cJ MGP_BALBcJ_G0020087
protein coding gene Chr12:110421142-110513227 (+)
C3H/HeJ MGP_C3HHeJ_G0019889
protein coding gene Chr12:113659088-113754687 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020532
protein coding gene Chr12:117959174-118052842 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018145
protein coding gene Chr12:106432998-106525917 (+)
CAST/EiJ MGP_CASTEiJ_G0019430
protein coding gene Chr12:108510187-108608496 (+)
CBA/J MGP_CBAJ_G0019856
protein coding gene Chr12:122463316-122563332 (+)
DBA/2J MGP_DBA2J_G0019973
protein coding gene Chr12:109479965-109575161 (+)
FVB/NJ MGP_FVBNJ_G0019958
protein coding gene Chr12:108290260-108379099 (+)
LP/J MGP_LPJ_G0020048
protein coding gene Chr12:114231494-114326332 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019996
protein coding gene Chr12:125556832-125656728 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020561
protein coding gene Chr12:112678843-112772743 (+)
PWK/PhJ MGP_PWKPhJ_G0019191
protein coding gene Chr12:104128955-104216892 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018994
protein coding gene Chr12:106835738-106931190 (+)
WSB/EiJ MGP_WSBEiJ_G0019489
protein coding gene Chr12:113584870-113677100 (+)



Homology
more
  • Human Ortholog
    TDRD9, tudor domain containing 9
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TDRD9, tudor domain containing 9
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C14orf75, HIG-1, HLS, NET54, SPGF30, SPNE
  • Links
    NCBI Gene ID: 122402
    neXtProt AC: NX_Q8NDG6
    UniProt: Q8NDG6

  • Chr Location
    14q32.33; chr14:103928343-104052667 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 14311
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TDRD9
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Male homozygous mice are sterile, displaying small testis, arrest of male meiosis and abnormal spermatocyte morphology. Females are fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000054003 Ensembl Gene Model | MGI Sequence Detail 97296 C57BL/6J ±  kb
    transcript ENSMUST00000079009 Ensembl | MGI Sequence Detail 4809 Not Applicable  
    polypeptide ENSMUSP00000078022 Ensembl | MGI Sequence Detail 1383 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 2
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 10
      Gene Ontology 8
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:261014 Yoshimura T, et al., Mouse GTSF1 is an essential factor for secondary piRNA biogenesis. EMBO Rep. 2018 Apr;19(4)

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/15/2019
    MGI 6.14
    The Jackson Laboratory