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Mroh2b Gene Detail
Summary
  • Symbol
    Mroh2b
  • Name
    maestro heat-like repeat family member 2B
  • Synonyms
    4930455B06Rik, Heatr7b2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921905
    NCBI Gene: 223825
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:4898737-4962205 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 1.98 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    215 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921905
protein coding gene Chr15:4898215-4962207 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021688
protein coding gene Chr15:1781931-1851901 (+)
A/J MGP_AJ_G0021648
protein coding gene Chr15:1800868-1862871 (+)
AKR/J MGP_AKRJ_G0021626
protein coding gene Chr15:1768410-1842015 (+)
BALB/cJ MGP_BALBcJ_G0021655
protein coding gene Chr15:1736451-1805131 (+)
C3H/HeJ MGP_C3HHeJ_G0021431
protein coding gene Chr15:1802499-1866667 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022094
protein coding gene Chr15:1865022-1927761 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019632
protein coding gene Chr15:1561004-1624489 (+)
CAST/EiJ MGP_CASTEiJ_G0020948
protein coding gene Chr15:1777625-1838364 (+)
CBA/J MGP_CBAJ_G0021400
protein coding gene Chr15:1903675-1972083 (+)
DBA/2J MGP_DBA2J_G0021524
protein coding gene Chr15:1742160-1808081 (+)
FVB/NJ MGP_FVBNJ_G0021502
protein coding gene Chr15:1686436-1749507 (+)
LP/J MGP_LPJ_G0021592
protein coding gene Chr15:1724267-1791098 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021528
protein coding gene Chr15:2022770-2091908 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022117
protein coding gene Chr15:1787670-1847743 (+)
PWK/PhJ MGP_PWKPhJ_G0020691
protein coding gene Chr15:1750031-1817641 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020529
protein coding gene Chr15:1754606-1820200 (+)
WSB/EiJ MGP_WSBEiJ_G0021003
protein coding gene Chr15:1723831-1792577 (+)



Homology
more
  • Human Ortholog
    MROH2B, maestro heat like repeat family member 2B
  • Vertebrate Orthologs
    58
  • Human Ortholog
    MROH2B, maestro heat like repeat family member 2B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HEATR7B2, SPIF
  • Links
    NCBI Gene ID: 133558
    neXtProt AC: NX_Q7Z745
    UniProt: Q7Z745

  • Chr Location
    5p13.1; chr5:40998020-41071342 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022155 Ensembl Gene Model | MGI Sequence Detail 63469 C57BL/6J ±  kb
transcript ENSMUST00000045736 Ensembl | MGI Sequence Detail 4829 Not Applicable  
polypeptide ENSMUSP00000036148 Ensembl | MGI Sequence Detail 1581 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:236944 Stanger SJ, et al., A novel germ cell protein, SPIF (sperm PKA interacting factor), is essential for the formation of a PKA/TCP11 complex that undergoes conformational and phosphorylation changes upon capacitation. FASEB J. 2016 Aug;30(8):2777-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory