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Spsb1 Gene Detail
Summary
  • Symbol
    Spsb1
  • Name
    splA/ryanodine receptor domain and SOCS box containing 1
  • Synonyms
    1110014L01Rik, 4930422J18Rik, SSB1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921896
    NCBI Gene: 74646
  • Gene Overview
    MyGene.info: SPSB1
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:149896283-149955006 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 80.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    488 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921896
protein coding gene Chr4:149896283-149955043 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029147
protein coding gene Chr4:153809737-153873930 (-)
A/J MGP_AJ_G0029112
protein coding gene Chr4:147367367-147427305 (-)
AKR/J MGP_AKRJ_G0029060
protein coding gene Chr4:151418055-151478739 (-)
BALB/cJ MGP_BALBcJ_G0029128
protein coding gene Chr4:147860848-147928442 (-)
C3H/HeJ MGP_C3HHeJ_G0028849
protein coding gene Chr4:151951589-152012450 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029577
protein coding gene Chr4:159351056-159417253 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026823
protein coding gene Chr4:139779302-139836884 (-)
CAST/EiJ MGP_CASTEiJ_G0028262
protein coding gene Chr4:149202508-149260711 (-)
CBA/J MGP_CBAJ_G0028811
protein coding gene Chr4:164025329-164097704 (-)
DBA/2J MGP_DBA2J_G0028960
protein coding gene Chr4:147466826-147525582 (-)
FVB/NJ MGP_FVBNJ_G0028924
protein coding gene Chr4:146587499-146647409 (-)
LP/J MGP_LPJ_G0029050
protein coding gene Chr4:153724813-153784568 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028951
protein coding gene Chr4:167220029-167283272 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029609
protein coding gene Chr4:151908281-151974037 (-)
PWK/PhJ MGP_PWKPhJ_G0027982
protein coding gene Chr4:143477955-143538467 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027816
protein coding gene Chr4:146166911-146229302 (-)
WSB/EiJ MGP_WSBEiJ_G0028342
protein coding gene Chr4:152055799-152117753 (-)



Homology
more
  • Human Ortholog
    SPSB1, splA/ryanodine receptor domain and SOCS box containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SPSB1, splA/ryanodine receptor domain and SOCS box containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SSB1, SSB-1
  • Links
    NCBI Gene ID: 80176
    neXtProt AC: NX_Q96BD6
    UniProt: Q96BD6

  • Chr Location
    1p36.22; chr1:9292882-9369532 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11832
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SPSB1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74646 NCBI Gene Model | MGI Sequence Detail 58724 C57BL/6J ±  kb
transcript NM_029035 RefSeq | MGI Sequence Detail 3089 C57BL/6  
polypeptide Q9D5L7 UniProt | EBI | MGI Sequence Detail 273 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 45
    cDNA 45

    Microarray probesets 9
Other
Accession IDs
less
MGI:1922029, MGI:2140339, MGI:2140398
References
more
  • Summaries
    All 44
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:241581 Shi W, et al., Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress. Blood. 2017 May 04;129(18):2479-2492

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory