Cds1
Gene Detail

Symbol

Name
ID

Cds1
CDP-diacylglycerol synthase 1
MGI:1921846

Synonyms

4833409J18Rik, phosphatidate cytidylyltransferase

Feature Type

protein coding gene

Genetic Map

Chromosome 5
48.93 cM, cytoband E3
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr5:101765130-101823858 bp, + strand From VEGA annotation of GRCm38   58729 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:68173  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: phosphatidate cytidylyltransferase, eukaryotic type
Gene Tree: Cds1

Human
homologs

Human Homolog		CDS1, CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
NCBI Gene ID		1040
neXtProt AC		NX_Q92903
Human Synonyms		CDS
Human Chr (Location)		4q21.23; chr4:84582904-84651340 (+)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(6) : Gene trapped(6)
Incidental mutations (data from Mutagenetix , APF )

Interactions

Cds1 interacts with 232 markers (Mir7-1, Mir7-2, Mir7b, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (16 annotations)

Process	CDP-diacylglycerol biosynthetic process, lipid metabolic process, ...
Component	endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function	nucleotidyltransferase activity, phosphatidate cytidylyltransferase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (7 records)

Data Summary: Results (382)    Tissues (138)    Images (54)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	375
Northern blot	7

cDNA source data(48)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(49) cDNA(49)
Microarray probesets(5)

Other database
links

VEGA Gene Model	OTTMUSG00000029627 (Evidence)
Ensembl Gene Model	ENSMUSG00000029330 (Evidence)
Entrez Gene	74596 (Evidence)
UniGene	46764
DFCI	TC1577464
DoTS	DT.482216
EC	2.7.7.41
Consensus CDS Project	CCDS19472.1
International Mouse Knockout Project Status	Cds1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000029627	VEGA Gene Model | MGI Sequence Detail	58729	C57BL/6J
transcript	OTTMUST00000073500	VEGA | MGI Sequence Detail	3924	Not Applicable
polypeptide	OTTMUSP00000038040	VEGA | MGI Sequence Detail	461	Not Applicable

All sequences(30) RefSeq(6) UniProt(1)

Polymorphisms

SNPs within 2kb(367 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR000374	Phosphatidate cytidylyltransferase
InterPro	IPR016720	Phosphatidate cytidylyltransferase, eukaryota
Protein Ontology	PR:000005290	phosphatidate cytidylyltransferase 1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(38)

Other
accession IDs

MGI:2140827, MGI:2141164