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Ppp6r3 Gene Detail
Summary
  • Symbol
    Ppp6r3
  • Name
    protein phosphatase 6, regulatory subunit 3
  • Synonyms
    4930528G08Rik, 9130026N02Rik, D19Bwg1430e, D19Ertd703e, mKIAA1558, Pp6r3, Pptcs3, Saps3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921807
    NCBI Gene: 52036
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:3454928-3575749 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 3.21 cM, cytoband A
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    462 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921807
protein coding gene Chr19:3454928-3575749 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024626
protein coding gene Chr19:215216-340244 (-)
A/J MGP_AJ_G0024593
protein coding gene Chr19:223071-346254 (-)
AKR/J MGP_AKRJ_G0024564
protein coding gene Chr19:210632-334351 (-)
BALB/cJ MGP_BALBcJ_G0024591
protein coding gene Chr19:208614-330400 (-)
C3H/HeJ MGP_C3HHeJ_G0024360
protein coding gene Chr19:213587-337426 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025039
protein coding gene Chr19:203485-328695 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022468
protein coding gene Chr19:201360-321802 (-)
CAST/EiJ MGP_CASTEiJ_G0023832
protein coding gene Chr19:211156-344182 (-)
CBA/J MGP_CBAJ_G0024330
protein coding gene Chr19:236795-371902 (-)
DBA/2J MGP_DBA2J_G0024459
protein coding gene Chr19:204583-325516 (-)
FVB/NJ MGP_FVBNJ_G0024426
protein coding gene Chr19:206088-329293 (-)
LP/J MGP_LPJ_G0024545
protein coding gene Chr19:213217-339092 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024456
protein coding gene Chr19:222827-361759 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025087
protein coding gene Chr19:203614-331513 (-)
PWK/PhJ MGP_PWKPhJ_G0023578
protein coding gene Chr19:214475-337097 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023384
protein coding gene Chr19:203948-330523 (-)
WSB/EiJ MGP_WSBEiJ_G0023895
protein coding gene Chr19:211893-333834 (-)



Homology
more
  • Human Ortholog
    PPP6R3, protein phosphatase 6 regulatory subunit 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PPP6R3, protein phosphatase 6 regulatory subunit 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C11orf23, PP6R3, SAP190, SAPL, SAPLa, SAPS3
  • Links
    NCBI Gene ID: 55291
    neXtProt AC: NX_Q5H9R7
    UniProt: Q5H9R7

  • Chr Location
    11q13.2; chr11:68460712-68615334 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52036 NCBI Gene Model | MGI Sequence Detail 120822 C57BL/6J ±  kb
transcript NM_001360429 RefSeq | MGI Sequence Detail 4997 C57BL/6  
polypeptide Q922D4 UniProt | EBI | MGI Sequence Detail 844 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR016024 Armadillo-type fold
    IPR007587 SIT4 phosphatase-associated protein family
Molecular
Reagents
less
  • All nucleic 286
    cDNA 284
    Primer pair 2

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-33943, MGI:106251, MGI:1097687, MGI:1289228, MGI:1923074
References
more
  • Summaries
    All 41
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:42329 Saijoh Y, et al., Identification of putative downstream genes of Oct-3, a pluripotent cell-specific transcription factor. Genes Cells. 1996 Feb;1(2):239-52
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory