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Nipal3
Gene Detail
 Symbol
Name
ID
Nipal3
NIPA-like domain containing 3
MGI:1921802
Synonyms 9130020G22Rik, Npal3
Feature Type protein coding gene
Genetic Map
Chromosome 4
67.64 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:135445420-135495038 bp, - strand
From VEGA annotation of GRCm38

  49619 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10722  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Nipal3

Human
homologs
Human Homolog NIPAL3, NIPA-like domain containing 3
NCBI Gene ID 57185
neXtProt AC  NX_Q6P499
Human Synonyms  DJ462O23.2, NPAL3
Human Chr (Location)  1p36.12-p35.1; chr1:24415750-24472983 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(34) : Gene trapped(33) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit gender-dependent behavioral and immune system abnormalities.
 
Interactions
Nipal3 interacts with 295 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process magnesium ion transport
Component integral component of membrane, membrane
Function magnesium ion transmembrane transporter activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (160)    Tissues (48)    Images (19)
Theiler Stages: 13, 15, 17, 19, 20, 21, 22, 23, 24, 25, 28
Assay TypeResults
RNA in situ 132
Northern blot 18
RT-PCR 10
cDNA source data(59)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(62) cDNA(61) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000009737 (Evidence)
Ensembl Gene ModelENSMUSG00000028803 (Evidence)
Entrez Gene74552 (Evidence)
UniGene26548
DFCITC1579859, TC1604323, TC1605637
DoTSDT.40181940
NIA Mouse Gene IndexU025658
Consensus CDS ProjectCCDS18786.1
International Mouse Knockout Project StatusNipal3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009737 VEGA Gene Model | MGI Sequence Detail 49619 C57BL/6J ±  kb
transcript OTTMUST00000022485 VEGA | MGI Sequence Detail 1956 Not Applicable 
polypeptide OTTMUSP00000065504 VEGA | MGI Sequence Detail 418 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(12) UniProt(5)
Polymorphisms SNPs within 2kb(393 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008521 Magnesium transporter NIPA
Protein Ontology PR:000011348 NIPA-like protein 3
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)
Other
accession IDs
MGI:2140306

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory