Mgme1
Gene Detail

Symbol Name ID

Mgme1 mitochondrial genome maintainance exonuclease 1 MGI:1921778

Synonyms

8430406I07Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 2

70.98 cM, cytoband H1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr2:144270663-144281227 bp, + strand From VEGA annotation of GRCm38   10565 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:12573  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 zebrafish

Gene Tree: Mgme1

Human homologs

Human Homolog		MGME1, mitochondrial genome maintenance exonuclease 1
NCBI Gene ID		92667
neXtProt AC		NX_Q9BQP7
Human Synonyms		bA504H3.4, C20orf72, DDK1, MTDPS11
Human Chr (Location)		20p11.23; chr20:17949762-17971761 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human MGME1

Alleles and phenotypes

All alleles(126) : Targeted(2) Gene trapped(124)

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	mitochondrial DNA repair, mitochondrial genome maintenance
Component	mitochondrion
Function	single-stranded DNA specific exodeoxyribonuclease activity

External Resources: FuncBase

Expression

cDNA source data(53)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(53) cDNA(53)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000003459 (Evidence)
Ensembl Gene Model	ENSMUSG00000027424 (Evidence)
Entrez Gene	74528 (Evidence)
UniGene	386817
DFCI	TC1579323
DoTS	DT.531162, DT.87049939, DT.97355510, DT.99852383
NIA Mouse Gene Index	U002567
Consensus CDS Project	CCDS16816.1
International Mouse Knockout Project Status	Mgme1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000003459	VEGA Gene Model | MGI Sequence Detail	10565	C57BL/6J
transcript	OTTMUST00000007325	VEGA | MGI Sequence Detail	2308	Not Applicable
polypeptide	OTTMUSP00000003534	VEGA | MGI Sequence Detail	338	Not Applicable

All sequences(37) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(54 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR026970	Uncharacterised protein C20orf72

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
All references(33)

Other accession IDs

MGI:2138936