About   Help   FAQ
Gorasp1 Gene Detail
Summary
  • Symbol
    Gorasp1
  • Name
    golgi reassembly stacking protein 1
  • Synonyms
    5430411C10Rik, GOLPH5, GRASP65, P65
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921748
    NCBI Gene: 74498
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:119754739-119766624 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 71.33 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    119 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921748
protein coding gene Chr9:119754323-119766631 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035426
protein coding gene Chr9:122733306-122747193 (-)
A/J MGP_AJ_G0035407
protein coding gene Chr9:118138473-118150368 (-)
AKR/J MGP_AKRJ_G0035339
protein coding gene Chr9:121232933-121244816 (-)
BALB/cJ MGP_BALBcJ_G0035402
protein coding gene Chr9:118026724-118038611 (-)
C3H/HeJ MGP_C3HHeJ_G0035110
protein coding gene Chr9:121700972-121713928 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035925
protein coding gene Chr9:126098593-126110482 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032808
protein coding gene Chr9:115344117-115356232 (-)
CAST/EiJ MGP_CASTEiJ_G0034415
protein coding gene Chr9:121708065-121720007 (-)
CBA/J MGP_CBAJ_G0035077
protein coding gene Chr9:130803003-130814889 (-)
DBA/2J MGP_DBA2J_G0035236
protein coding gene Chr9:117590341-117602227 (-)
FVB/NJ MGP_FVBNJ_G0035183
protein coding gene Chr9:116468289-116480180 (-)
LP/J MGP_LPJ_G0035315
protein coding gene Chr9:123070682-123082582 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035225
protein coding gene Chr9:131741293-131753174 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035945
protein coding gene Chr9:121621514-121633399 (-)
PWK/PhJ MGP_PWKPhJ_G0034120
protein coding gene Chr9:118025934-118037993 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033956
protein coding gene Chr9:121707533-121723435 (-)
WSB/EiJ MGP_WSBEiJ_G0034535
protein coding gene Chr9:121506144-121519412 (-)



Homology
more
  • Human Ortholog
    GORASP1, golgi reassembly stacking protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GORASP1, golgi reassembly stacking protein 1
  • Synonyms
    GOLPH5, GRASP65, P65
  • Links
    NCBI Gene ID: 64689
    neXtProt AC: NX_Q9BQQ3
    UniProt: Q9BQQ3

  • Chr Location
    3p22.2; chr3:39095222-39108369 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted disruption of this gene are viable, fertile and healthy with no detectable tissue defects. However, immortalized mutant embryonic fibroblasts show loss of cis Golgi integrity and glycosylation defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74498 NCBI Gene Model | MGI Sequence Detail 11886 C57BL/6J ±  kb
    transcript NM_028976 RefSeq | MGI Sequence Detail 3483 C57BL/6  
    polypeptide Q91X51 UniProt | EBI | MGI Sequence Detail 446 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 4
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 4
      Gene Ontology 9
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:301041 Guo D, et al., Ontogenesis of the tear drainage system requires Prickle1-driven polarized basement membrane deposition. Development. 2020 Nov 30;147(22):dev191726

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.
    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory