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Taf7l
Gene Detail
 Symbol
Name
ID
Taf7l
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor
MGI:1921719
Synonyms 4933438I11Rik, Taf2q
Feature Type protein coding gene
Genetic Map
Chromosome X
56.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:134460118-134476490 bp, - strand
From VEGA annotation of GRCm38

  16373 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:83311  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Taf7l

Human
homologs
Human Homolog TAF7L, TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
NCBI Gene ID 54457
neXtProt AC  NX_Q5H9L4
Human Synonyms  CT40, TAF2Q
Human Chr (Location)  Xq22.1; chrX:101268253-101293071 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF )
 
Mice homozygous for a null allele display reduced male fertility, oligozoospermia, teratozoospermia, athenozoospermia, abnormal seminiferous tubules, and reduced testes weight on congenic but not on mixed strain backgrounds.
 
Interactions
Taf7l interacts with 94 markers (Mir7-1, Mir30a, Mir30d, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell differentiation, multicellular organismal development, ...
Component cytoplasm, nucleus, ...
Function protein binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (24)    Tissues (15)    Images (2)
Theiler Stages: 23
Assay TypeResults
RNA in situ 24
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(18) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000019305 (Evidence)
Ensembl Gene ModelENSMUSG00000009596 (Evidence)
Entrez Gene74469 (Evidence)
UniGene103259
DFCITC1586655
DoTSDT.87072169
NIA Mouse Gene IndexU039700
Consensus CDS ProjectCCDS53184.1
International Mouse Knockout Project StatusTaf7l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019305 VEGA Gene Model | MGI Sequence Detail 16373 C57BL/6J ±  kb
transcript OTTMUST00000046133 VEGA | MGI Sequence Detail 1933 Not Applicable 
polypeptide OTTMUSP00000020831 VEGA | MGI Sequence Detail 471 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(14) UniProt(2)
Polymorphisms SNPs within 2kb(30 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006751 TAFII55 protein, conserved region
Protein Ontology PR:000016034 transcription initiation factor TFIID subunit 7-like
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:201992 Zhou H, et al., Taf7l cooperates with Trf2 to regulate spermiogenesis. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16886-91
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory