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Hyal5 Gene Detail
Summary
  • Symbol
    Hyal5
  • Name
    hyaluronoglucosaminidase 5
  • Synonyms
    4933439A12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921718
    NCBI Gene: 74468
  • Gene Overview
    MyGene.info: SPAM1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:24857997-24891958 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 11.28 cM, cytoband A3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    95 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921718
protein coding gene Chr6:24857962-24891958 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030501
protein coding gene Chr6:22422279-22454753 (+)
A/J MGP_AJ_G0030474
protein coding gene Chr6:21490560-21520664 (+)
AKR/J MGP_AKRJ_G0030401
protein coding gene Chr6:22186904-22219355 (+)
BALB/cJ MGP_BALBcJ_G0030484
protein coding gene Chr6:21609374-21639180 (+)
C3H/HeJ MGP_C3HHeJ_G0030197
protein coding gene Chr6:22181826-22223467 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030938
protein coding gene Chr6:23124786-23159195 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028149
protein coding gene Chr6:19938069-19958019 (+)
CAST/EiJ MGP_CASTEiJ_G0029599
protein coding gene Chr6:22043184-22076688 (+)
CBA/J MGP_CBAJ_G0030175
protein coding gene Chr6:23910447-23951718 (+)
DBA/2J MGP_DBA2J_G0030319
protein coding gene Chr6:21454298-21490848 (+)
FVB/NJ MGP_FVBNJ_G0030273
protein coding gene Chr6:21205487-21237453 (+)
LP/J MGP_LPJ_G0030406
protein coding gene Chr6:22580937-22616394 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030309
protein coding gene Chr6:25875940-25916919 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030968
protein coding gene Chr6:22109783-22144599 (+)
PWK/PhJ MGP_PWKPhJ_G0029313
protein coding gene Chr6:21017334-21049554 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029149
protein coding gene Chr6:21827659-21858116 (+)
WSB/EiJ MGP_WSBEiJ_G0029675
protein coding gene Chr6:22075128-22109361 (+)



Homology
more
  • Human Ortholog
    SPAM1, sperm adhesion molecule 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SPAM1, sperm adhesion molecule 1
    Orthology source: HomoloGene
  • Synonyms
    HEL-S-96n, HYA1, HYAL1, HYAL3, HYAL5, PH20, PH-20, SPAG15
  • Links
    NCBI Gene ID: 6677
    neXtProt AC: NX_P38567
    UniProt: P38567

  • Chr Location
    7q31.32; chr7:123925232-123971410 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotype references
Reproduction is normal in mice with null mutations at this marker.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029678 Ensembl Gene Model | MGI Sequence Detail 33962 C57BL/6J ±  kb
transcript ENSMUST00000200968 Ensembl | MGI Sequence Detail 2070 Not Applicable  
polypeptide ENSMUSP00000144011 Ensembl | MGI Sequence Detail 526 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory