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Sohlh2
Gene Detail
Symbol

Name
ID
Sohlh2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
MGI:1921684
Synonyms
4933406N12Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 3
26.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:55182028-55209957 bp, + strand
From VEGA annotation of GRCm38

  27930 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9864  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Sohlh2

Human
homologs
Human Homolog CCDC169-SOHLH2, CCDC169-SOHLH2 readthrough
NCBI Gene ID 100526761
neXtProt AC  NX_Q9NX45
Human Synonyms  C13orf38-SOHLH2
Human Chr (Location)  13q; chr13:36168208-36297855 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit male and female sterility associated with testis and ovary degeneration.
 
Interactions
Sohlh2 interacts with 152 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process cell differentiation, multicellular organismal development, ...
Component nucleus
Function DNA binding, protein dimerization activity, ...
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (223)    Tissues (135)    Images (63)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 38
RNA in situ 112
Western blot 5
RT-PCR 68
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(9) Primer pair(6) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000023038 (Evidence)
Ensembl Gene ModelENSMUSG00000027794 (Evidence)
Entrez Gene74434 (Evidence)
UniGene25514
DFCITC1587499
DoTSDT.40155108
NIA Mouse Gene IndexU003245
Consensus CDS ProjectCCDS17358.1
International Mouse Knockout Project StatusSohlh2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023038 VEGA Gene Model | MGI Sequence Detail 27930 C57BL/6J ±  kb
transcript OTTMUST00000055515 VEGA | MGI Sequence Detail 2364 Not Applicable 
polypeptide OTTMUSP00000026590 VEGA | MGI Sequence Detail 467 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(214 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Protein Ontology PR:000015403 spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(43)
Other
accession IDs
MGI:2139689

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory