About   Help   FAQ
Tc2n Gene Detail
Summary
  • Symbol
    Tc2n
  • Name
    tandem C2 domains, nuclear
  • Synonyms
    4933406D09Rik, Mtac2d1, Tac2-N
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921663
    NCBI Gene: 74413
  • Gene Overview
    MyGene.info: TC2N
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:101645443-101718523 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 51.26 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    363 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921663
protein coding gene Chr12:101645443-101719002 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020024
protein coding gene Chr12:103235149-103306468 (-)
A/J MGP_AJ_G0019980
protein coding gene Chr12:99274394-99347484 (-)
AKR/J MGP_AKRJ_G0019956
protein coding gene Chr12:102100494-102171923 (-)
BALB/cJ MGP_BALBcJ_G0019966
protein coding gene Chr12:99627912-99694658 (-)
C3H/HeJ MGP_C3HHeJ_G0019768
protein coding gene Chr12:102536619-102622666 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020415
protein coding gene Chr12:106470290-106551304 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0019314
protein coding gene Chr12:97374675-97452273 (-)
CBA/J MGP_CBAJ_G0019740
protein coding gene Chr12:110400865-110475943 (-)
DBA/2J MGP_DBA2J_G0019851
protein coding gene Chr12:98806295-98874145 (-)
FVB/NJ MGP_FVBNJ_G0019840
protein coding gene Chr12:97519537-97587875 (-)
LP/J MGP_LPJ_G0019927
protein coding gene Chr12:103100994-103177455 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020444
protein coding gene Chr12:101612125-101685221 (-)
PWK/PhJ MGP_PWKPhJ_G0019077
protein coding gene Chr12:93352998-93429392 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018873
protein coding gene Chr12:95777858-95859469 (-)
WSB/EiJ MGP_WSBEiJ_G0019368
protein coding gene Chr12:102487504-102562647 (-)



Homology
more
  • Human Ortholog
    TC2N, tandem C2 domains, nuclear
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TC2N, tandem C2 domains, nuclear
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C14orf47, C2CD1, MTAC2D1, Tac2-N
  • Links
    NCBI Gene ID: 123036
    neXtProt AC: NX_Q8N9U0
    UniProt: Q8N9U0

  • Chr Location
    14q32.12; chr14:91779751-91867536 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 12560
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TC2N
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021187 Ensembl Gene Model | MGI Sequence Detail 73081 C57BL/6J ±  kb
transcript ENSMUST00000162735 Ensembl | MGI Sequence Detail 5290 Not Applicable  
polypeptide ENSMUSP00000125288 Ensembl | MGI Sequence Detail 489 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 5
References
more
  • Summaries
    All 22
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory