About   Help   FAQ
Gle1
Gene Detail
Symbol

Name
ID
Gle1
GLE1 RNA export mediator (yeast)
MGI:1921662
Synonyms
4933405K21Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
20.88 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:29935426-29960371 bp, + strand
From VEGA annotation of GRCm38

  24946 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20379  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GLE1
Gene Tree: Gle1

Human
homologs
GLE1, GLE1 RNA export mediator
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 2733
neXtProt AC: NX_Q53GS7

Human Synonyms: GLE1L, hGLE1, LCCS, LCCS1

Human Chr (Location): 9q34.11; chr9:128504692-128542301 (+)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human GLE1

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(11) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Gle1 interacts with 284 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process mRNA transport, poly(A)+ mRNA export from nucleus, ...
Component cytoplasm, extracellular space, ...
Function identical protein binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (22)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 20
RT-PCR 2
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase gle1 ; ZFIN gle1    NEW 
Molecular
reagents
All nucleic(15) cDNA(14) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000016705 (Evidence)
Ensembl Gene Model ENSMUSG00000019715 (Evidence)
Entrez Gene 74412 (Evidence)
DFCI TC1678041, TC1657500, TC1631816, TC1574551, TC1605130
DoTS DT.55168295, DT.110720386, DT.101273951, DT.110720360, DT.94369904, DT.91404841, DT.60100229
NIA Mouse Gene Index U001569
Consensus CDS Project CCDS15862.1
International Mouse Phenotyping Consortium Status Gle1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016705 VEGA Gene Model | MGI Sequence Detail 24946 C57BL/6J ±  kb
transcript OTTMUST00000040476 VEGA | MGI Sequence Detail 4030 Not Applicable 
polypeptide OTTMUSP00000018090 VEGA | MGI Sequence Detail 699 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(52 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012476 GLE1-like
Protein Ontology PR:000008024 nucleoporin GLE1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)
Other
accession IDs
MGI:2138794

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/30/2015
MGI 5.22
The Jackson Laboratory