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Efhc2 Gene Detail
Summary
  • Symbol
    Efhc2
  • Name
    EF-hand domain (C-terminal) containing 2
  • Synonyms
    4933407D04Rik, mRib72-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921655
    NCBI Gene: 74405
  • Gene Overview
    MyGene.info: EFHC2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:17132049-17319368 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 12.34 cM, cytoband A1.3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    431 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921655
protein coding gene ChrX:17132049-17320470 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035582
protein coding gene ChrX:12005548-12197850 (-)
A/J MGP_AJ_G0035559
protein coding gene ChrX:12110836-12306715 (-)
AKR/J MGP_AKRJ_G0035491
protein coding gene ChrX:12484866-12676381 (-)
BALB/cJ MGP_BALBcJ_G0035552
protein coding gene ChrX:11896895-12088019 (-)
C3H/HeJ MGP_C3HHeJ_G0035269
protein coding gene ChrX:12134083-12326839 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036087
protein coding gene ChrX:12287261-12501170 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032952
protein coding gene ChrX:10638753-10822049 (-)
CAST/EiJ MGP_CASTEiJ_G0034561
protein coding gene ChrX:11679642-11870602 (-)
CBA/J MGP_CBAJ_G0035238
protein coding gene ChrX:12859417-13065135 (-)
DBA/2J MGP_DBA2J_G0035390
protein coding gene ChrX:11927894-12115798 (-)
FVB/NJ MGP_FVBNJ_G0035337
protein coding gene ChrX:11809609-11995114 (-)
LP/J MGP_LPJ_G0035472
protein coding gene ChrX:12289179-12501269 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035381
protein coding gene ChrX:13005679-13219565 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036094
protein coding gene ChrX:11918011-12114237 (-)
PWK/PhJ MGP_PWKPhJ_G0034262
protein coding gene ChrX:11250720-11442108 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034101
protein coding gene ChrX:11943693-12149249 (-)
WSB/EiJ MGP_WSBEiJ_G0034696
protein coding gene ChrX:11889995-12078908 (-)



Homology
more
  • Human Ortholog
    EFHC2, EF-hand domain containing 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EFHC2, EF-hand domain containing 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    dJ1158H2.1, MRX74
  • Links
    NCBI Gene ID: 80258
    neXtProt AC: NX_Q5JST6
    UniProt: Q5JST6

  • Chr Location
    Xp11.3; chrX:44146254-44343677 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11863
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: EFHC2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025038 Ensembl Gene Model | MGI Sequence Detail 187320 C57BL/6J ±  kb
transcript ENSMUST00000026014 Ensembl | MGI Sequence Detail 2554 Not Applicable  
polypeptide ENSMUSP00000026014 Ensembl | MGI Sequence Detail 750 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory