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Terb2 Gene Detail
Summary
  • Symbol
    Terb2
  • Name
    telomere repeat binding bouquet formation protein 2
  • Synonyms
    4933406J08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921651
    NCBI Gene: 74401
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:122016753-122036874 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.56 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    239 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921651
 protein coding gene Chr2:122016753-122036878 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026408
 protein coding gene Chr2:125175296-125194688 (+)
A/J MGP_AJ_G0026370
 protein coding gene Chr2:120058746-120077625 (+)
AKR/J MGP_AKRJ_G0026347
 protein coding gene Chr2:123422702-123441544 (+)
BALB/cJ MGP_BALBcJ_G0026382
 protein coding gene Chr2:120294041-120312686 (+)
C3H/HeJ MGP_C3HHeJ_G0026127
 protein coding gene Chr2:123908205-123926818 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026829
 protein coding gene Chr2:129236993-129258737 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024208
 protein coding gene Chr2:115032809-115051012 (+)
CAST/EiJ MGP_CASTEiJ_G0025589
 protein coding gene Chr2:124243970-124262466 (+)
CBA/J MGP_CBAJ_G0026106
 protein coding gene Chr2:133793638-133812462 (+)
DBA/2J MGP_DBA2J_G0026243
 protein coding gene Chr2:119458246-119477018 (+)
FVB/NJ MGP_FVBNJ_G0026205
 protein coding gene Chr2:118247999-118266827 (+)
LP/J MGP_LPJ_G0026345
 protein coding gene Chr2:125428504-125448106 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026225
 protein coding gene Chr2:138003270-138024905 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026884
 protein coding gene Chr2:123539247-123558102 (+)
PWK/PhJ MGP_PWKPhJ_G0025325
 protein coding gene Chr2:119067847-119088153 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025125
 protein coding gene Chr2:122679040-122701642 (+)
WSB/EiJ MGP_WSBEiJ_G0025661
 protein coding gene Chr2:124396205-124416633 (+)



Homology
more
  • Human Ortholog
    TERB2, telomere repeat binding bouquet formation protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TERB2, telomere repeat binding bouquet formation protein 2
  • Synonyms
    C15orf43, SPGF59
  • Links
    NCBI Gene ID: 145645
    neXtProt AC: NX_Q8NHR7
    UniProt: Q8NHR7

  • Chr Location
    15q21.1; chr15:44956687-44979229 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TERB2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit sterility due to arrested meiosis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74401 NCBI Gene Model | MGI Sequence Detail 20122 C57BL/6J ±  kb
    transcript NM_028914 RefSeq | MGI Sequence Detail 2111 C57BL/6  
    polypeptide Q9D494 UniProt | EBI | MGI Sequence Detail 218 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000059965 telomere repeats-binding bouquet formation protein 2
      (term hierarchy)
    • InterPro Domains
      IPR028065 Telomere repeats-binding bouquet formation protein 2
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 2
    References
    more
    • Summaries
      All 26
      Gene Ontology 3
      Phenotypes 9
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:346053 Zhang J, et al., Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2. Nat Commun. 2024 Mar 14;15(1):2315
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory