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Rmi1 Gene Detail
Summary
  • Symbol
    Rmi1
  • Name
    RecQ mediated genome instability 1
  • Synonyms
    4932432N11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921636
    NCBI Gene: 74386
  • Gene Overview
    MyGene.info: RMI1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:58402248-58411148 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 31.05 cM, cytoband B2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921636
protein coding gene Chr13:58402248-58411149 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020634
protein coding gene Chr13:58042763-58051324 (+)
A/J MGP_AJ_G0020588
protein coding gene Chr13:55889670-55898228 (+)
AKR/J MGP_AKRJ_G0020566
protein coding gene Chr13:57551940-57560492 (+)
BALB/cJ MGP_BALBcJ_G0020584
protein coding gene Chr13:56148248-56156762 (+)
C3H/HeJ MGP_C3HHeJ_G0020383
protein coding gene Chr13:57359367-57368090 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021018
protein coding gene Chr13:59825330-59833883 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018600
protein coding gene Chr13:53781318-53789575 (+)
CAST/EiJ MGP_CASTEiJ_G0019897
protein coding gene Chr13:57492382-57503729 (+)
CBA/J MGP_CBAJ_G0020343
protein coding gene Chr13:62074480-62083037 (+)
DBA/2J MGP_DBA2J_G0020466
protein coding gene Chr13:55439524-55448075 (+)
FVB/NJ MGP_FVBNJ_G0020445
protein coding gene Chr13:54916512-54925156 (+)
LP/J MGP_LPJ_G0020542
protein coding gene Chr13:58314543-58323075 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020474
protein coding gene Chr13:61433981-61442533 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021061
protein coding gene Chr13:57155914-57168463 (+)
PWK/PhJ MGP_PWKPhJ_G0019653
protein coding gene Chr13:55447393-55456194 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019480
protein coding gene Chr13:56065286-56073917 (+)
WSB/EiJ MGP_WSBEiJ_G0019959
protein coding gene Chr13:57589100-57599502 (+)



Homology
more
  • Human Ortholog
    RMI1, RecQ mediated genome instability 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RMI1, RecQ mediated genome instability 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BLAP75, C9orf76, FAAP75
  • Links
    NCBI Gene ID: 80010
    neXtProt AC: NX_Q9H9A7
    UniProt: Q9H9A7

  • Chr Location
    9q21.32; chr9:83980722-84004074 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41601
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RMI1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    8 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele exhibit decreased weight and increased resistance to diet-induced obesity.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035367 Ensembl Gene Model | MGI Sequence Detail 8901 C57BL/6J ±  kb
transcript ENSMUST00000225828 Ensembl | MGI Sequence Detail 3594 Not Applicable  
polypeptide ENSMUSP00000153675 Ensembl | MGI Sequence Detail 616 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000014036 RecQ-mediated genome instability protein 1
  • InterPro Domains
    IPR039215 RecQ-mediated genome instability protein 1
    IPR032199 Recq-mediated genome instability protein 1, C-terminal OB-fold domain
    IPR033472 RecQ mediated genome instability protein, DUF1767
    IPR013894 RecQ mediated genome instability protein, N-terminal
Molecular
Reagents
less
  • All nucleic 48
    cDNA 48

    Microarray probesets 6
Other
Accession IDs
less
MGI:2145511
References
more
  • Summaries
    All 35
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory