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Rmi1
Gene Detail
Symbol

Name
ID
Rmi1
RMI1, RecQ mediated genome instability 1
MGI:1921636
Synonyms
4932432N11Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 13
31.05 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:58402597-58411149 bp, + strand
From Ensembl annotation of GRCm38

  8553 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41601  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RMI1
Gene Tree: Rmi1

Human
homologs
RMI1, RecQ mediated genome instability 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 80010
neXtProt AC: NX_Q9H9A7

Human Synonyms: BLAP75, C9orf76, FAAP75

Human Chr (Location): 9q21.32; chr9:83980720-84004074 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(16)
Incidental mutations (data from APF , CvDC )
 
Mice homozygous for a gene trapped allele exhibit decreased weight and increased resistance to diet-induced obesity.
 
Interactions
Rmi1 interacts with 241 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process DNA replication, glucose homeostasis, ...
Component nucleoplasm, nucleus
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(47)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rmi1 ; ZFIN rmi1    NEW 
Molecular
reagents
All nucleic(47) cDNA(47)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000035367 (Evidence)
Entrez Gene 74386 (Evidence)
UniGene 85289
DFCI TC1579500, TC1614637, TC1645167
NIA Mouse Gene Index U356730, U014922
Consensus CDS Project CCDS26571.1
International Mouse Phenotyping Consortium Status Rmi1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035367 Ensembl Gene Model | MGI Sequence Detail 8553 C57BL/6J ±  kb
transcript ENSMUST00000042450 Ensembl | MGI Sequence Detail 3522 Not Applicable 
polypeptide ENSMUSP00000041035 Ensembl | MGI Sequence Detail 616 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(7) UniProt(1)
Polymorphisms
SNPs within 2kb(39 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013894 Domain of unknown function DUF1767
Protein Ontology PR:000014036 RecQ-mediated genome instability protein 1
References
(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:168271 Suwa A, et al., RMI1 deficiency in mice protects from diet and genetic-induced obesity. FEBS J. 2010 Feb;277(3):677-86
All references(30)
Other
accession IDs
MGI:2145511

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory