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Ap5m1 Gene Detail
Summary
  • Symbol
    Ap5m1
  • Name
    adaptor-related protein complex 5, mu 1 subunit
  • Synonyms
    4932432K03Rik, Mudeng
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921635
    NCBI Gene: 74385
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:49066495-49094113 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 25.36 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    299 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921635
protein coding gene Chr14:49066097-49094234 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021229
protein coding gene Chr14:42967230-42987983 (+)
A/J MGP_AJ_G0021178
protein coding gene Chr14:41608298-41629412 (+)
AKR/J MGP_AKRJ_G0021156
protein coding gene Chr14:43231946-43253061 (+)
BALB/cJ MGP_BALBcJ_G0021181
protein coding gene Chr14:41656498-41677453 (+)
C3H/HeJ MGP_C3HHeJ_G0020964
protein coding gene Chr14:43012161-43033262 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021616
protein coding gene Chr14:44724999-44747138 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019175
protein coding gene Chr14:40909718-40930791 (+)
CAST/EiJ MGP_CASTEiJ_G0020490
protein coding gene Chr14:40156154-40176813 (+)
CBA/J MGP_CBAJ_G0020931
protein coding gene Chr14:46163590-46184237 (+)
DBA/2J MGP_DBA2J_G0021054
protein coding gene Chr14:41481013-41504387 (+)
FVB/NJ MGP_FVBNJ_G0021039
protein coding gene Chr14:41225449-41246035 (+)
LP/J MGP_LPJ_G0021123
protein coding gene Chr14:43220694-43241311 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021064
protein coding gene Chr14:45484707-45506353 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021649
protein coding gene Chr14:42764580-42787649 (+)
PWK/PhJ MGP_PWKPhJ_G0020238
protein coding gene Chr14:38386234-38407372 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020063
protein coding gene Chr14:38880373-38901447 (+)
WSB/EiJ MGP_WSBEiJ_G0020546
protein coding gene Chr14:42869976-42891184 (+)



Homology
more
  • Human Ortholog
    AP5M1, adaptor related protein complex 5 subunit mu 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AP5M1, adaptor related protein complex 5 subunit mu 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C14orf108, Mu5, MuD, MUDENG
  • Links
    NCBI Gene ID: 55745
    neXtProt AC: NX_Q9H0R1
    UniProt: Q9H0R1

  • Chr Location
    14q22.3; chr14:57268888-57298742 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10081
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: AP5M1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    15
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    11
  • Targeted
    2
  • Genomic Mutations
    1 involving Ap5m1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74385 NCBI Gene Model | MGI Sequence Detail 27619 C57BL/6J ±  kb
transcript NM_001360070 RefSeq | MGI Sequence Detail 3898 C57BL/6  
polypeptide Q8BJ63 UniProt | EBI | MGI Sequence Detail 490 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 61
    cDNA 61

    Microarray probesets 6
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory