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Ubap2l Gene Detail
Summary
  • Symbol
    Ubap2l
  • Name
    ubiquitin-associated protein 2-like
  • Synonyms
    3110083O19Rik, 4932431F02Rik, A430103N23Rik, mKIAA0144, NICE-4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921633
    NCBI Gene: 74383
  • Gene Overview
    MyGene.info: UBAP2L
Location & Maps
more
  • Sequence Map
    Chr3:90000140-90052628 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      52489 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 39.19 cM, cytoband F2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    UBAP2L, ubiquitin associated protein 2 like
  • Vertebrate Orthologs
    3
  • Human Ortholog
    UBAP2L, ubiquitin associated protein 2 like
    Orthology source: HGNC
  • Synonyms
    NICE4, NICE-4
  • Links
    NCBI Gene ID: 9898
    neXtProt AC: NX_Q14157

  • Chr Location
    1q21.3; chr1:154219951-154271510 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    57
  • Chemically induced (other)
    1
  • Gene trapped
    51
  • Radiation induced
    1
  • Targeted
    3
  • Transgenic
    1
  • Genomic Mutations
    2 involving Ubap2l
  • Incidental Mutations
Mice homozygous for a transgenic gene disruption exhibit decreased female body size and reduced female fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000052888 VEGA Gene Model | MGI Sequence Detail 52489 C57BL/6J ±  kb
transcript OTTMUST00000132359 VEGA | MGI Sequence Detail 4073 Not Applicable  
polypeptide OTTMUSP00000070574 VEGA | MGI Sequence Detail 1112 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    67 from dbSNP Build 142
Protein
Information
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  • UniProt
    15 Sequences
  • Protein Ontology
    PR:000016960 ubiquitin-associated protein 2-like
  • PDB
  • InterPro Domains
    IPR022166 Protein of unknown function DUF3697, ubiquitin-associated protein 2
    IPR009060 UBA-like
    IPR015940 Ubiquitin-associated domain
Molecular
Reagents
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  • All nucleic 29
    cDNA 29

    Microarray probesets 6
Other
Accession IDs
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MGI:1920486, MGI:1924440, MGI:2140046
References
more
  • Summaries
    All 34
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:218697 Bordeleau ME, et al., UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity. Blood. 2014 Oct 9;124(15):2362-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory