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Hsf2bp Gene Detail
Summary
  • Symbol
    Hsf2bp
  • Name
    heat shock transcription factor 2 binding protein
  • Synonyms
    4932437G14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921627
    NCBI Gene: 74377
Location & Maps
more
  • Sequence Map
    Chr17:31944769-32034508 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      89740 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 17.25 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    HSF2BP, heat shock transcription factor 2 binding protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HSF2BP, heat shock transcription factor 2 binding protein
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 11077
    neXtProt AC: NX_O75031

  • Chr Location
    21q22.3; chr21:43529186-43659499 (-)  GRCh38.p2

Human Diseases
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  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    16
  • Gene trapped
    11
  • Targeted
    5
  • Genomic Mutations
    2 involving Hsf2bp
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031368 VEGA Gene Model | MGI Sequence Detail 89740 C57BL/6J ±  kb
transcript OTTMUST00000077724 VEGA | MGI Sequence Detail 2867 Not Applicable  
polypeptide OTTMUSP00000041175 VEGA | MGI Sequence Detail 338 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    426 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR016024 Armadillo-type fold
Molecular
Reagents
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  • All nucleic 16
    Genomic 1
    cDNA 13
    Primer pair 2

    Microarray probesets 6
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Diseases 2
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:198994 Wu Y, et al., HSF2BP represses BNC1 transcriptional activity by sequestering BNC1 to the cytoplasm. FEBS Lett. 2013 Jul 11;587(14):2099-104

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory