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Tmed5 Gene Detail
Summary
  • Symbol
    Tmed5
  • Name
    transmembrane emp24 protein transport domain containing 5
  • Synonyms
    3110020O18Rik, 4432412D15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921586
    NCBI Gene: 73130
Location & Maps
more
  • Sequence Map
    Chr5:108106366-108132620 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26255 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 52.49 cM, cytoband E5
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TMED5, transmembrane p24 trafficking protein 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMED5, transmembrane p24 trafficking protein 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CGI-100, p24g2, p28
  • Links
    NCBI Gene ID: 50999
    neXtProt AC: NX_Q9Y3A6

  • Chr Location
    1p22.1; chr1:93149742-93180689 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 4996
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: TMED5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    10
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Tmed5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028919 VEGA Gene Model | MGI Sequence Detail 26255 C57BL/6J ±  kb
transcript OTTMUST00000071669 VEGA | MGI Sequence Detail 3800 Not Applicable  
polypeptide OTTMUSP00000036770 VEGA | MGI Sequence Detail 229 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    199 from dbSNP Build 142
Protein
Information
less
  • UniProt
    11 Sequences
  • Protein Ontology
    PR:000030597 transmembrane emp24 domain-containing protein 5
  • InterPro Domains
    IPR009038 GOLD domain
    IPR015720 TMP21-related
    IPR015717 Transmembrane emp24 domain-containing protein 5
Molecular
Reagents
less
  • All nucleic 114
    cDNA 114

    Microarray probesets 7
Other
Accession IDs
less
MGI:1920380
References
more
  • Summaries
    All 27
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory