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Xrcc3
Gene Detail
Symbol

Name
ID
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
MGI:1921585
Synonyms
4432412E01Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 12
61.14 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:111803192-111813873 bp, - strand
From VEGA annotation of GRCm38

  10682 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36178  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: DNA repair and recombination protein, Rad51 type
Gene Tree: Xrcc3

Human
homologs
Human Homolog XRCC3, X-ray repair complementing defective repair in Chinese hamster cells 3
NCBI Gene ID 7517
neXtProt AC  NX_O43542
Human Synonyms  CMM6
Human Chr (Location)  14q32.3; chr14:103697608-103715486 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human XRCC3
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Xrcc3 interacts with 184 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (1)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(21)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000027508 (Evidence)
Ensembl Gene ModelENSMUSG00000021287 (Evidence)
Entrez Gene74335 (Evidence)
UniGene19082
DFCITC1596520, TC1581854
DoTSDT.99855581, DT.94259435, DT.482384
NIA Mouse Gene IndexU034377
Consensus CDS ProjectCCDS26187.1
International Mouse Knockout Project StatusXrcc3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027508 VEGA Gene Model | MGI Sequence Detail 10682 C57BL/6J ±  kb
transcript OTTMUST00000068090 VEGA | MGI Sequence Detail 2422 Not Applicable 
polypeptide OTTMUSP00000034360 VEGA | MGI Sequence Detail 349 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(173 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013632 DNA recombination and repair protein Rad51, C-terminal
InterPro IPR016467 DNA recombination and repair protein, RecA-like
InterPro IPR020588 DNA recombination/repair protein RecA/RadB, ATP-binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000017506 DNA repair protein XRCC3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(31)
Other
accession IDs
MGI:2144770, MGI:2145034

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory