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Ranbp10 Gene Detail
Summary
  • Symbol
    Ranbp10
  • Name
    RAN binding protein 10
  • Synonyms
    4432417N03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921584
    NCBI Gene: 74334
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:105768308-105827350 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    198 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921584
protein coding gene Chr8:105768308-105827350 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034059
protein coding gene Chr8:108081088-108141821 (-)
A/J MGP_AJ_G0034040
protein coding gene Chr8:103755886-103818371 (-)
AKR/J MGP_AKRJ_G0033966
protein coding gene Chr8:106756257-106814534 (-)
BALB/cJ MGP_BALBcJ_G0034033
protein coding gene Chr8:103946850-104007190 (-)
C3H/HeJ MGP_C3HHeJ_G0033745
protein coding gene Chr8:107500387-107562538 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034553
protein coding gene Chr8:112045863-112112592 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031495
protein coding gene Chr8:96893943-96960100 (-)
CAST/EiJ MGP_CASTEiJ_G0033071
protein coding gene Chr8:107005523-107075691 (-)
CBA/J MGP_CBAJ_G0033718
protein coding gene Chr8:115639302-115712842 (-)
DBA/2J MGP_DBA2J_G0033873
protein coding gene Chr8:103105336-103165318 (-)
FVB/NJ MGP_FVBNJ_G0033819
protein coding gene Chr8:102032462-102095415 (-)
LP/J MGP_LPJ_G0033964
protein coding gene Chr8:108281478-108351527 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033862
protein coding gene Chr8:118844703-118911988 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034571
protein coding gene Chr8:106721067-106782572 (-)
PWK/PhJ MGP_PWKPhJ_G0032772
protein coding gene Chr8:102500685-102567328 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032613
protein coding gene Chr8:105417479-105476516 (-)
WSB/EiJ MGP_WSBEiJ_G0033187
protein coding gene Chr8:107405133-107470652 (-)



Homology
more
  • Human Ortholog
    RANBP10, RAN binding protein 10
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RANBP10, RAN binding protein 10
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 57610
    neXtProt AC: NX_Q6VN20
    UniProt: Q6VN20

  • Chr Location
    16q22.1; chr16:67723066-67806652 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit slight defects in erythrocyte number and volume, decreased platelet aggregattion and increased bleeding time associated with impaired platelet dense granule release.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74334 NCBI Gene Model | MGI Sequence Detail 59043 C57BL/6J ±  kb
    transcript NM_145824 RefSeq | MGI Sequence Detail 5166 C57BL/6  
    polypeptide Q6VN19 UniProt | EBI | MGI Sequence Detail 620 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 108
      cDNA 107
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:62506 Hemberger M, et al., cDNA subtraction cloning reveals novel genes whose temporal and spatial expression indicates association with trophoblast invasion. Dev Biol. 2000 Jun 1;222(1):158-69
    • Latest
      J:192924 Meyer I, et al., Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10. Blood. 2012 Oct 25;120(17):3594-602

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    03/13/2019
    MGI 6.13
    The Jackson Laboratory