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Dnajc14 Gene Detail
Summary
  • Symbol
    Dnajc14
  • Name
    DnaJ heat shock protein family (Hsp40) member C14
  • Synonyms
    5730551F12Rik, DRIP78, HDJ3, LIP6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921580
    NCBI Gene: 74330
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:128641423-128655317 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 77.16 cM, cytoband D3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    241 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921580
 protein coding gene Chr10:128639931-128655317 (+)
129S1/SvImJ ENSMUSG00200012346
 protein coding gene Chr10:124998057-125013444 (+)
A/J ENSMUSG00195014134
 protein coding gene Chr10:125461355-125476744 (+)
AKR/J ENSMUSG00220005242
 protein coding gene Chr10:125066291-125081691 (+)
BALB/cJ ENSMUSG00180009242
 protein coding gene Chr10:125452335-125467723 (+)
C3H/HeJ ENSMUSG00175005567
 protein coding gene Chr10:125451526-125466929 (+)
C57BL/6NJ ENSMUSG00215010922
 protein coding gene Chr10:125058447-125073835 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015956
 protein coding gene Chr10:121174252-121186303 (+)
CAST/EiJ ENSTCUG00005039646
 protein coding gene Chr10:124444545-124458039 (+)
CBA/J ENSMUSG00210007720
 protein coding gene Chr10:125275744-125291144 (+)
DBA/2J ENSMUSG00185024921
 protein coding gene Chr10:125425504-125440890 (+)
FVB/NJ ENSMUSG00205014801
 protein coding gene Chr10:124666935-124682321 (+)
JF1/MsJ ENSUMUG00000038495
 protein coding gene Chr10:126735454-126749345 (+)
LP/J ENSMUSG00230032002
 protein coding gene Chr10:127351022-127366413 (+)
NOD/ShiLtJ ENSMUSG00190014864
 protein coding gene Chr10:125489136-125504522 (+)
NZO/HlLtJ ENSMUSG00225036651
 protein coding gene Chr10:131550078-131565462 (+)
PWK/PhJ ENSLUMG00010009659
 protein coding gene Chr10:125192201-125206090 (+)
SPRET/EiJ ENSMSPG00010029905
 protein coding gene Chr10:127147202-127163906 (+)
WSB/EiJ ENSIUOG00005008516
 protein coding gene Chr10:125072612-125087996 (+)



Homology
more
  • Human Ortholog
    DNAJC14, DnaJ heat shock protein family (Hsp40) member C14
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DNAJC14, DnaJ heat shock protein family (Hsp40) member C14
  • Synonyms
    DNAJ, DRIP78, HDJ3, LIP6
  • Links
    NCBI Gene ID: 85406
    UniProt: Q6Y2X3

  • Chr Location
    12q13.2; chr12:55820746-55830824 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    654
  • Tissues
    46
  • cDNA Data
    12
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74330 NCBI Gene Model | MGI Sequence Detail 13895 C57BL/6J ±  kb
    transcript NM_001359825 RefSeq | MGI Sequence Detail 4329 C57BL/6  
    polypeptide Q921R4 UniProt | EBI | MGI Sequence Detail 703 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 12

      Microarray probesets 5
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory