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Inava Gene Detail
Summary
  • Symbol
    Inava
  • Name
    innate immunity activator
  • Synonyms
    1700034M08Rik, 5730559C18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921579
    NCBI Gene: 67313
  • Gene Overview
    MyGene.info: INAVA
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:136213531-136234264 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 59.61 cM, cytoband F
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    183 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921579
protein coding gene Chr1:136213522-136234293 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016538
protein coding gene Chr1:140029064-140049828 (-)
A/J MGP_AJ_G0016521
protein coding gene Chr1:134721532-134742253 (-)
AKR/J MGP_AKRJ_G0016486
protein coding gene Chr1:138726446-138747177 (-)
BALB/cJ MGP_BALBcJ_G0016481
protein coding gene Chr1:135050856-135072156 (-)
C3H/HeJ MGP_C3HHeJ_G0016307
protein coding gene Chr1:138822118-138842757 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016942
protein coding gene Chr1:145048769-145069487 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014653
protein coding gene Chr1:127829169-127849845 (-)
CAST/EiJ MGP_CASTEiJ_G0015887
protein coding gene Chr1:137922657-137943372 (-)
CBA/J MGP_CBAJ_G0016280
protein coding gene Chr1:150071653-150092364 (-)
DBA/2J MGP_DBA2J_G0016386
protein coding gene Chr1:133715009-133735827 (-)
FVB/NJ MGP_FVBNJ_G0016385
protein coding gene Chr1:132363415-132384501 (-)
LP/J MGP_LPJ_G0016457
protein coding gene Chr1:141248806-141269563 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016410
protein coding gene Chr1:155714632-155735384 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016978
protein coding gene Chr1:138491267-138511850 (-)
PWK/PhJ MGP_PWKPhJ_G0015673
protein coding gene Chr1:132764463-132785488 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015460
protein coding gene Chr1:137483553-137504122 (-)
WSB/EiJ MGP_WSBEiJ_G0015950
protein coding gene Chr1:138535288-138556053 (-)



Homology
more
  • Human Ortholog
    INAVA, innate immunity activator
  • Vertebrate Orthologs
    7
  • Human Ortholog
    INAVA, innate immunity activator
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C1orf106
  • Links
    NCBI Gene ID: 55765
    neXtProt AC: NX_Q3KP66
    UniProt: Q3KP66

  • Chr Location
    1q32.1; chr1:200891074-200915736 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041605 Ensembl Gene Model | MGI Sequence Detail 20734 C57BL/6J ±  kb
transcript ENSMUST00000120339 Ensembl | MGI Sequence Detail 2988 Not Applicable  
polypeptide ENSMUSP00000113785 Ensembl | MGI Sequence Detail 677 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR021774 Domain of unknown function DUF3338
    IPR039106 Innate immunity activator protein
Molecular
Reagents
less
  • All nucleic 34
    Genomic 1
    cDNA 33

    Microarray probesets 4
Other
Accession IDs
less
MGI:1914563
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:257317 Mohanan V, et al., C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions. Science. 2018 Mar 9;359(6380):1161-1166

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/27/2018
MGI 6.13
The Jackson Laboratory