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Cltb Gene Detail
Summary
  • Symbol
    Cltb
  • Name
    clathrin, light polypeptide (Lcb)
  • Synonyms
    2310046E19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921575
    NCBI Gene: 74325
  • Gene Overview
    MyGene.info: CLTB
Location & Maps
more
  • Sequence Map
    Chr13:54592401-54611344 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      18944 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 28.84 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CLTB, clathrin light chain B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CLTB, clathrin light chain B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    LCB
  • Links
    NCBI Gene ID: 1212
    neXtProt AC: NX_P09497

  • Chr Location
    5q35; chr5:176392455-176416569 (-)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    54
  • Chemically induced (other)
    1
  • Gene trapped
    47
  • Targeted
    6
  • Genomic Mutations
    2 involving Cltb
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032678 VEGA Gene Model | MGI Sequence Detail 18944 C57BL/6J ±  kb
transcript OTTMUST00000081306 VEGA | MGI Sequence Detail 1004 Not Applicable  
polypeptide OTTMUSP00000043471 VEGA | MGI Sequence Detail 229 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    94 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000005613 clathrin light chain B
  • InterPro Domains
    IPR000996 Clathrin light chain
Molecular
Reagents
less
  • All nucleic 97
    cDNA 97

    Microarray probesets 5
References
more
  • Summaries
    All 38
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:213437 Storbeck M, et al., Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory