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Prss46
Gene Detail
 Symbol
Name
ID
Prss46
protease, serine 46
MGI:1921556
Synonyms 1700112C13Rik
Feature Type protein coding gene
Genetic Map
Chromosome 9
60.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:110844506-110856522 bp, + strand
From VEGA annotation of GRCm38

  12017 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77706  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

Protein SuperFamily: trypsin
Gene Tree: Prss46

Human
homologs
Human Homolog PRSS46, protease, serine, 46
NCBI Gene ID 100287362
neXtProt AC  NX_E5RG02
Human Synonyms  TESSP6
Human Chr (Location)  chr3:46719583-46736431 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(20) : Gene trapped(18) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prss46 interacts with 50 markers (Mir19b-1, Mir19b-2, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process proteolysis
Component integral component of membrane, membrane
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000031766 (Evidence)
Ensembl Gene ModelENSMUSG00000049719 (Evidence)
Entrez Gene74306 (Evidence)
UniGene87419
DFCITC1587607
DoTSDT.101162778, DT.60102287
NIA Mouse Gene IndexU011074
EC3.4.21.-
Consensus CDS ProjectCCDS23576.2
International Mouse Knockout Project StatusPrss46
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031766 VEGA Gene Model | MGI Sequence Detail 12017 C57BL/6J ±  kb
transcript OTTMUST00000078699 VEGA | MGI Sequence Detail 1257 Not Applicable 
polypeptide OTTMUSP00000041886 VEGA | MGI Sequence Detail 314 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(61 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000035339 serine protease 46
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory