Prss46
Gene Detail

Symbol Name ID

Prss46 protease, serine, 46 MGI:1921556

Synonyms

1700112C13Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 9

60.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr9:110844506-110856522 bp, + strand From VEGA annotation of GRCm38   12017 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:77706  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 dog

Protein SuperFamily: trypsin
Gene Tree: Prss46

Human homologs

Human Homolog		PRSS46, protease, serine, 46
NCBI Gene ID		100287362
neXtProt AC		NX_E5RG02
Human Synonyms		TESSP6
Human Chr (Location)		chr3:46761073-46777921 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(20) : Targeted(2) Gene trapped(18)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	proteolysis
Component	integral to membrane, membrane
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(4) cDNA(4)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000031766 (Evidence)
Ensembl Gene Model	ENSMUSG00000049719 (Evidence)
Entrez Gene	74306 (Evidence)
UniGene	87419
DFCI	TC1587607
DoTS	DT.101162778, DT.60102287
NIA Mouse Gene Index	U011074
EC	3.4.21.-
Consensus CDS Project	CCDS23576.2
International Mouse Knockout Project Status	Prss46

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031766	VEGA Gene Model | MGI Sequence Detail	12017	C57BL/6J
transcript	OTTMUST00000078699	VEGA | MGI Sequence Detail	1257	Not Applicable
polypeptide	OTTMUSP00000041886	VEGA | MGI Sequence Detail	314	Not Applicable

All sequences(22) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(12 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site
Protein Ontology	PR:000035339	serine protease 46

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)