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Mtmr3
Gene Detail
Symbol

Name
ID
Mtmr3
myotubularin related protein 3
MGI:1921552
Synonyms
1700092A20Rik, FYVE-DSP1, mKIAA0371, ZFYVE10
Feature Type
protein coding gene
Genetic Map
Chromosome 11
2.94 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:4480875-4594863 bp, - strand
From VEGA annotation of GRCm38

  113989 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23662  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Mtmr3

Human
homologs
Human Homolog MTMR3, myotubularin related protein 3
NCBI Gene ID 8897
neXtProt AC  NX_Q13615
Human Synonyms  FYVE-DSP1, ZFYVE10
Human Chr (Location)  22q12.2; chr22:29883160-30030868 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(19) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in increased serum alkaline phosphatase level and, in males, impaired glucose tolerance.
 
Interactions
Mtmr3 interacts with 317 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process dephosphorylation, lipid metabolic process, ...
Component cytoplasm, extrinsic component of membrane, ...
Function hydrolase activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (169)    Tissues (101)    Images (36)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 156
RT-PCR 13
cDNA source data(160)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(161) cDNA(160) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000005070 (Evidence)
Ensembl Gene ModelENSMUSG00000034354 (Evidence)
Entrez Gene74302 (Evidence)
UniGene425669
DFCITC1616390, TC1607109, TC1577237, TC1631670
DoTSDT.97384092, DT.491749, DT.110505405, DT.91386146
NIA Mouse Gene IndexU032447
EC3.1.3.64, 3.1.3.48, 3.1.3.95
Consensus CDS ProjectCCDS48744.1
International Mouse Knockout Project StatusMtmr3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005070 VEGA Gene Model | MGI Sequence Detail 113989 C57BL/6J ±  kb
transcript OTTMUST00000011299 VEGA | MGI Sequence Detail 5466 Not Applicable 
polypeptide OTTMUSP00000005266 VEGA | MGI Sequence Detail 1195 Not Applicable 

For the selected sequences
All sequences(85) RefSeq(11) UniProt(17)
Polymorphisms
SNPs within 2kb(319 from dbSNP Build 137)    SNPs within 2kb including multiple locations(321)
Protein-related
information
ResourceIDDescription
InterPro IPR010569 Myotubularin-related
InterPro IPR016130 Protein-tyrosine phosphatase, active site
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR017455 Zinc finger, FYVE-related
InterPro IPR000306 Zinc finger, FYVE-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000010737 myotubularin-related protein 3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(42)
Other
accession IDs
MGI:2144089, MGI:2144577

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory