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Spem1
Gene Detail
Symbol

Name
ID
Spem1
sperm maturation 1
MGI:1921538
Synonyms
1700095G12Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
42.89 cM, cytoband B4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:69820876-69822180 bp, - strand
From VEGA annotation of GRCm38

  1305 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45717  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: SPEM1
Gene Tree: Spem1

Human
homologs
SPEM1, spermatid maturation 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 374768
neXtProt AC: NX_Q8N4L4

Human Synonyms: C17orf83

Human Chr (Location): 17p13.1; chr17:7420360-7421632 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Genomic Mutations involving Spem1 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Male mice homozygous for a null allele display infertility, asthenozoospermia, teratozoospermia, and impaired spermiogenesis.
 
Phenotype Images(2)
Interactions
Spem1 interacts with 8 markers (Mir29b-1, Mir29b-2, Mir207, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process cell differentiation, multicellular organismal development, ...
Component cytoplasm, integral component of membrane, ...
External Resources: FuncBase
Expression
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000005997 (Evidence)
Ensembl Gene Model ENSMUSG00000041165 (Evidence)
Entrez Gene 74288 (Evidence)
UniGene 159159
DFCI TC1588731
DoTS DT.40142862
NIA Mouse Gene Index U032983
Consensus CDS Project CCDS36199.1
International Mouse Phenotyping Consortium Status Spem1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005997 VEGA Gene Model | MGI Sequence Detail 1305 C57BL/6J ±  kb
transcript OTTMUST00000013424 VEGA | MGI Sequence Detail 1041 Not Applicable 
polypeptide OTTMUSP00000006213 VEGA | MGI Sequence Detail 310 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(3) UniProt(1)
Polymorphisms
SNPs within 2kb(26 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000015513 spermatid maturation protein 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:179469 Bao J, et al., RANBP17 is localized to the XY body of spermatocytes and interacts with SPEM1 on the manchette of elongating spermatids. Mol Cell Endocrinol. 2011 Feb 20;333(2):134-42
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory