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Chic2 Gene Detail
Summary
  • Symbol
    Chic2
  • Name
    cysteine-rich hydrophobic domain 2
  • Synonyms
    1700081B18Rik, 4930502K01Rik, BTL
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921527
    NCBI Gene: 74277
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr5:74997988-75044774 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      46787 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 39.54 cM, cytoband D
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CHIC2, cysteine rich hydrophobic domain 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CHIC2, cysteine rich hydrophobic domain 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BTL
  • Links
    NCBI Gene ID: 26511
    neXtProt AC: NX_Q9UKJ5
    UniProt: Q9UKJ5

  • Chr Location
    4q12; chr4:53996335-54064648 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8105
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CHIC2
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    256 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000031089 VEGA Gene Model | MGI Sequence Detail 46787 C57BL/6J ±  kb
    transcript OTTMUST00000077019 VEGA | MGI Sequence Detail 9699 Not Applicable  
    polypeptide OTTMUSP00000040617 VEGA | MGI Sequence Detail 165 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      173 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 77
      cDNA 77

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1922202
    References
    more
    • Summaries
      All 280
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 3
      Phenotypes 256
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:260256 Zoltowska Nilsson AM, et al., Mast cell-dependent IL-33/ST2 signaling is protective against the development of airway hyperresponsiveness in a house dust mite mouse model of asthma. Am J Physiol Lung Cell Mol Physiol. 2018 Mar 1;314(3):L484-L492

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory