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Gale
Gene Detail
Symbol

Name
ID
Gale
galactose-4-epimerase, UDP
MGI:1921496
Synonyms
2310002A12Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 4
68.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:135963727-135968178 bp, + strand
From VEGA annotation of GRCm38

  4452 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:347  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GALE
Protein SuperFamily: UDP-glucose 4-epimerase
Gene Tree: Gale

Human
homologs
GALE, UDP-galactose-4-epimerase
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 2582
neXtProt AC: NX_Q14376

Human Synonyms: SDR1E1

Human Chr (Location): 1p36-p35; chr1:23795599-23800804 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human GALE

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(3) Targeted(4)
Genomic Mutations involving Gale (1)
Incidental mutations (data from APF , CvDC )
Interactions
Gale interacts with 76 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process carbohydrate metabolic process, galactose catabolic process, ...
Component extracellular exosome
Function catalytic activity, coenzyme binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (335)    Tissues (122)    Images (40)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 335
cDNA source data(72)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase gale ; ZFIN gale    NEW 
Molecular
reagents
All nucleic(73) cDNA(72) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000009851 (Evidence)
Ensembl Gene Model ENSMUSG00000028671 (Evidence)
Entrez Gene 74246 (Evidence)
UniGene 247946
DFCI TC1575414
DoTS DT.97359303, DT.489125, DT.110841873, DT.101398250
NIA Mouse Gene Index U004957
EC 5.1.3.7, 5.1.3.2
Consensus CDS Project CCDS18796.1
International Mouse Phenotyping Consortium Status Gale
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009851 VEGA Gene Model | MGI Sequence Detail 4452 C57BL/6J ±  kb
transcript OTTMUST00000022836 VEGA | MGI Sequence Detail 1430 Not Applicable 
polypeptide OTTMUSP00000010415 VEGA | MGI Sequence Detail 347 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(10) UniProt(3)
Polymorphisms
SNPs within 2kb(47 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001509 NAD-dependent epimerase/dehydratase
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR008089 Nucleotide sugar epimerase
InterPro IPR025308 UDP-glucose 4-epimerase C-terminal domain
InterPro IPR005886 UDP-glucose 4-epimerase GalE
Protein Ontology PR:000007812 UDP-glucose 4-epimerase
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)
Other
accession IDs
MGI:2140236

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory