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Gale
Gene Detail
Symbol

Name
ID
Gale
galactose-4-epimerase, UDP
MGI:1921496
Synonyms
2310002A12Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 4
68.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:135963727-135968178 bp, + strand
From VEGA annotation of GRCm38

  4452 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:347  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: UDP-glucose 4-epimerase
Gene Tree: Gale

Human
homologs
Human Homolog GALE, UDP-galactose-4-epimerase
NCBI Gene ID 2582
neXtProt AC  NX_Q14376
Human Synonyms  SDR1E1
Human Chr (Location)  1p36-p35; chr1:23795599-23800804 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human GALE
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from APF )
Interactions
Gale interacts with 76 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process carbohydrate metabolic process, galactose catabolic process, ...
Component extracellular vesicular exosome
Function catalytic activity, coenzyme binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (335)    Tissues (122)    Images (40)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 335
cDNA source data(72)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(73) cDNA(72) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000009851 (Evidence)
Ensembl Gene ModelENSMUSG00000028671 (Evidence)
Entrez Gene74246 (Evidence)
UniGene247946
DFCITC1575414
DoTSDT.101398250, DT.110841873, DT.489125, DT.97359303
NIA Mouse Gene IndexU004957
EC5.1.3.2
Consensus CDS ProjectCCDS18796.1
International Mouse Knockout Project StatusGale
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009851 VEGA Gene Model | MGI Sequence Detail 4452 C57BL/6J ±  kb
transcript OTTMUST00000022836 VEGA | MGI Sequence Detail 1430 Not Applicable 
polypeptide OTTMUSP00000010415 VEGA | MGI Sequence Detail 347 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(10) UniProt(3)
Polymorphisms
SNPs within 2kb(47 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001509 NAD-dependent epimerase/dehydratase
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR008089 Nucleotide sugar epimerase
InterPro IPR025308 UDP-glucose 4-epimerase C-terminal domain
InterPro IPR005886 UDP-glucose 4-epimerase GalE
Protein Ontology PR:000007812 UDP-glucose 4-epimerase
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)
Other
accession IDs
MGI:2140236

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory