Gale
Gene Detail

Symbol Name ID

Gale galactose-4-epimerase, UDP MGI:1921496

Synonyms

2310002A12Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 4

68.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr4:135963727-135968178 bp, + strand From VEGA annotation of GRCm38   4452 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:347  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: UDP-glucose 4-epimerase
Gene Tree: Gale

Human homologs

Human Homolog		GALE, UDP-galactose-4-epimerase
NCBI Gene ID		2582
neXtProt AC		NX_Q14376
Human Synonyms		SDR1E1
Human Chr (Location)		1p36-p35; chr1:24122089-24127294 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human GALE

Alleles and phenotypes

All alleles(4) : Targeted(1) Gene trapped(3)

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	carbohydrate metabolic process, cellular metabolic process, ...
Component	cellular_component
Function	catalytic activity, coenzyme binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (335)    Tissues (122)    Images (40)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	335

cDNA source data(72)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(73) cDNA(72) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000009851 (Evidence)
Ensembl Gene Model	ENSMUSG00000028671 (Evidence)
Entrez Gene	74246 (Evidence)
UniGene	247946
DFCI	TC1575414
DoTS	DT.101398250, DT.110841873, DT.489125, DT.97359303
NIA Mouse Gene Index	U004957
EC	5.1.3.2
Consensus CDS Project	CCDS18796.1
International Mouse Knockout Project Status	Gale

Sequences

Length	Strain/Species
genomic	OTTMUSG00000009851	VEGA Gene Model | MGI Sequence Detail	4452	C57BL/6J
transcript	OTTMUST00000022836	VEGA | MGI Sequence Detail	1430	Not Applicable
polypeptide	OTTMUSP00000010415	VEGA | MGI Sequence Detail	347	Not Applicable

All sequences(46) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(18 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001509	NAD-dependent epimerase/dehydratase
InterPro	IPR016040	NAD(P)-binding domain
InterPro	IPR008089	Nucleotide sugar epimerase
InterPro	IPR005886	UDP-glucose 4-epimerase
InterPro	IPR025308	UDP-glucose 4-epimerase C-terminal domain
Protein Ontology	PR:000007812	UDP-glucose 4-epimerase

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)

Other accession IDs

MGI:2140236