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Mterf2
Gene Detail
Symbol

Name
ID
Mterf2
mitochondrial transcription termination factor 2
MGI:1921488
Synonyms
1700007D05Rik, Mterfd3
Feature Type
protein coding gene
Genetic Map
Chromosome 10
41.63 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:85119435-85128027 bp, - strand
From Ensembl annotation of GRCm38

  8593 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11869  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Mterf2

Human
homologs
Human Homolog MTERF2, mitochondrial transcription termination factor 2
NCBI Gene ID 80298
neXtProt AC  NX_Q49AM1
Human Synonyms  MTERFD3, mTERFL
Human Chr (Location)  12q24.1; chr12:106977291-106987166 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(3) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene-trapped allele gain less weight than wild-type controls, develop a myopathy, and show memory deficits, decreased levels of mitochondrial transcripts, an imbalanced tRNA pool, impaired oxidative phosphorylation, reduced respiratory function, and enlarged mitochondrial mass.
 
Interactions
Mterf2 interacts with 33 markers (Mir29b-1, Mir29b-2, Mir128-1, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000049038 (Evidence)
Entrez Gene74238 (Evidence)
UniGene255401
DFCITC1589703, TC1610837, TC1617696, TC1698293
DoTSDT.524191, DT.91327938
NIA Mouse Gene IndexU032081
Consensus CDS ProjectCCDS24088.1
International Mouse Knockout Project StatusMterf2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049038 Ensembl Gene Model | MGI Sequence Detail 8593 C57BL/6J ±  kb
transcript ENSMUST00000050813 Ensembl | MGI Sequence Detail 1565 Not Applicable 
polypeptide ENSMUSP00000062762 Ensembl | MGI Sequence Detail 385 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(10) UniProt(1)
Polymorphisms
SNPs within 2kb(71 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003690 Mitochodrial transcription termination factor-related
Protein Ontology PR:000010716 mTERF domain-containing protein 3, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory