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Paqr8 Gene Detail
Summary
  • Symbol
    Paqr8
  • Name
    progestin and adipoQ receptor family member VIII
  • Synonyms
    1700019B16Rik, 3110001D06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921479
    NCBI Gene: 74229
  • Gene Overview
    MyGene.info: PAQR8
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:20960830-21009874 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 6.50 cM, cytoband A5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    658 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921479
protein coding gene Chr1:20960772-21009874 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015873
protein coding gene Chr1:18519269-18568437 (+)
A/J MGP_AJ_G0015854
protein coding gene Chr1:18300901-18348535 (+)
AKR/J MGP_AKRJ_G0015813
protein coding gene Chr1:18337502-18386048 (+)
BALB/cJ MGP_BALBcJ_G0015810
protein coding gene Chr1:17993328-18041276 (+)
C3H/HeJ MGP_C3HHeJ_G0015644
protein coding gene Chr1:18362629-18410200 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016264
protein coding gene Chr1:19389255-19437153 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013985
protein coding gene Chr1:16436867-16485764 (+)
CAST/EiJ MGP_CASTEiJ_G0015225
protein coding gene Chr1:18455412-18505953 (+)
CBA/J MGP_CBAJ_G0015617
protein coding gene Chr1:19831937-19881615 (+)
DBA/2J MGP_DBA2J_G0015716
protein coding gene Chr1:17794419-17841994 (+)
FVB/NJ MGP_FVBNJ_G0015721
protein coding gene Chr1:17555154-17604181 (+)
LP/J MGP_LPJ_G0015788
protein coding gene Chr1:18743914-18794214 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015739
protein coding gene Chr1:20778947-20828267 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016311
protein coding gene Chr1:18311968-18363740 (+)
PWK/PhJ MGP_PWKPhJ_G0015009
protein coding gene Chr1:17527515-17576133 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014790
protein coding gene Chr1:18405356-18453057 (+)
WSB/EiJ MGP_WSBEiJ_G0015288
protein coding gene Chr1:18243844-18293979 (+)



Homology
more
  • Human Ortholog
    PAQR8, progestin and adipoQ receptor family member 8
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PAQR8, progestin and adipoQ receptor family member 8
  • Synonyms
    C6orf33, LMPB1, MPRB
  • Links
    NCBI Gene ID: 85315
    neXtProt AC: NX_Q8TEZ7
    UniProt: Q8TEZ7

  • Chr Location
    6p12.2; chr6:52362128-52407777 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000025931 Ensembl Gene Model | MGI Sequence Detail 49045 C57BL/6J ±  kb
    transcript ENSMUST00000167119 Ensembl | MGI Sequence Detail 1472 Not Applicable  
    polypeptide ENSMUSP00000128781 Ensembl | MGI Sequence Detail 354 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 42
      cDNA 42

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1916512
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:286462 Dong Y, et al., Genome-Wide Off-Target Analysis in CRISPR-Cas9 Modified Mice and Their Offspring. G3 (Bethesda). 2019 Nov 5;9(11):3645-3651

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/19/2021
    MGI 6.17
    The Jackson Laboratory