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Eif4enif1 Gene Detail
Summary
  • Symbol
    Eif4enif1
  • Name
    eukaryotic translation initiation factor 4E nuclear import factor 1
  • Synonyms
    2610509L04Rik, A930019J01Rik, Clast4, D11Ertd166e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921453
    NCBI Gene: 74203
  • Gene Overview
    MyGene.info: EIF4ENIF1
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:3202392-3244588 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 2.24 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    91 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921453
protein coding gene Chr11:3201743-3244588 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017952
protein coding gene Chr11:47515-91587 (+)
A/J MGP_AJ_G0017925
protein coding gene Chr11:110168-152422 (+)
AKR/J MGP_AKRJ_G0017889
protein coding gene Chr11:98831-161998 (+)
BALB/cJ MGP_BALBcJ_G0017893
protein coding gene Chr11:85706-127639 (+)
C3H/HeJ MGP_C3HHeJ_G0017706
protein coding gene Chr11:49643-101059 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018346
protein coding gene Chr11:95560-154557 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016005
protein coding gene Chr11:30585-74899 (+)
CAST/EiJ MGP_CASTEiJ_G0017268
protein coding gene Chr11:1762-49145 (+)
CBA/J MGP_CBAJ_G0017681
protein coding gene Chr11:274072-317813 (+)
DBA/2J MGP_DBA2J_G0017792
protein coding gene Chr11:36804-79401 (+)
FVB/NJ MGP_FVBNJ_G0017783
protein coding gene Chr11:60035-104090 (+)
LP/J MGP_LPJ_G0017862
protein coding gene Chr11:150545-195856 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017809
protein coding gene Chr11:33883-75094 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018385
protein coding gene Chr11:125016-169232 (+)
PWK/PhJ MGP_PWKPhJ_G0017048
protein coding gene Chr11:7944-48670 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016844
protein coding gene Chr11:71204-119074 (+)
WSB/EiJ MGP_WSBEiJ_G0017322
protein coding gene Chr11:2436-45857 (+)



Homology
more
  • Human Ortholog
    EIF4ENIF1, eukaryotic translation initiation factor 4E nuclear import factor 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    EIF4ENIF1, eukaryotic translation initiation factor 4E nuclear import factor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    4E-T, Clast4
  • Links
    NCBI Gene ID: 56478
    neXtProt AC: NX_Q9NRA8
    UniProt: Q9NRA8

  • Chr Location
    22q12.2; chr22:31436963-31489950 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020454 Ensembl Gene Model | MGI Sequence Detail 42197 C57BL/6J ±  kb
transcript ENSMUST00000110049 Ensembl | MGI Sequence Detail 3614 Not Applicable  
polypeptide ENSMUSP00000105676 Ensembl | MGI Sequence Detail 983 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000006997 eukaryotic translation initiation factor 4E transporter
  • InterPro Domains
    IPR018862 Eukaryotic translation initiation factor 4E binding protein
Molecular
Reagents
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  • All nucleic 141
    cDNA 136
    Primer pair 5

    Microarray probesets 4
Other
Accession IDs
less
MGI:1098834, MGI:1925202, MGI:2144007, MGI:2144407
References
more
  • Summaries
    All 43
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:240319 Stauber M, et al., Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory