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Gtf2e1
Gene Detail
Symbol

Name
ID
Gtf2e1
general transcription factor II E, polypeptide 1 (alpha subunit)
MGI:1921447
Synonyms
2610024P03Rik, 56kDa, FE, TFIIE-A
Feature Type
protein coding gene
Genetic Map
Chromosome 16
26.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:37509790-37539789 bp, - strand
From VEGA annotation of GRCm38

  30000 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38062  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Gtf2e1

Human
homologs
Human Homolog GTF2E1, general transcription factor IIE, polypeptide 1, alpha 56kDa
NCBI Gene ID 2960
neXtProt AC  NX_P29083
Human Synonyms  FE, TF2E1, TFIIE-A
Human Chr (Location)  3q21-q24; chr3:120742711-120783069 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(25) : Gene trapped(22) Targeted(3)
Incidental mutations (data from APF )
Interactions
Gtf2e1 interacts with 228 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (126)    Tissues (117)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 118
RT-PCR 8
cDNA source data(59)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(62) cDNA(60) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000025449 (Evidence)
Ensembl Gene ModelENSMUSG00000022828 (Evidence)
Entrez Gene74197 (Evidence)
UniGene287795
DFCITC1609373, TC1575437
DoTSDT.528621, DT.97361847
NIA Mouse Gene IndexU037027
Consensus CDS ProjectCCDS28160.1
International Mouse Knockout Project StatusGtf2e1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025449 VEGA Gene Model | MGI Sequence Detail 30000 C57BL/6J ±  kb
transcript OTTMUST00000062666 VEGA | MGI Sequence Detail 3084 Not Applicable 
polypeptide OTTMUSP00000030935 VEGA | MGI Sequence Detail 440 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(180 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain
InterPro IPR017919 Transcription factor TFE/TFIIEalpha HTH domain
InterPro IPR002853 Transcription factor TFIIE, alpha subunit
InterPro IPR021600 Transcription factor TFIIE alpha subunit, C-terminal
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR013137 Zinc finger, TFIIB-type
Protein Ontology PR:000008314 general transcription factor IIE subunit 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:181994 Kamileri I, et al., Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2995-3000
All references(45)
Other
accession IDs
MGI:2146403

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory