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Gtf2e1 Gene Detail
Summary
  • Symbol
    Gtf2e1
  • Name
    general transcription factor II E, polypeptide 1 (alpha subunit)
  • Synonyms
    2610024P03Rik, 56kDa, FE, TFIIE-A
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921447
    NCBI Gene: 74197
  • Gene Overview
    MyGene.info: GTF2E1
Location & Maps
more
  • Sequence Map
    Chr16:37509790-37539789 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30000 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 26.38 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    GTF2E1, general transcription factor IIE subunit 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GTF2E1, general transcription factor IIE subunit 1
    Orthology source: HomoloGene
  • Synonyms
    FE, TF2E1, TFIIE-A
  • Links
    NCBI Gene ID: 2960
    neXtProt AC: NX_P29083

  • Chr Location
    3q21-q24; chr3:120742711-120783070 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    25
  • Gene trapped
    22
  • Targeted
    3
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025449 VEGA Gene Model | MGI Sequence Detail 30000 C57BL/6J ±  kb
transcript OTTMUST00000062666 VEGA | MGI Sequence Detail 3084 Not Applicable  
polypeptide OTTMUSP00000030935 VEGA | MGI Sequence Detail 440 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    179 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000008314 general transcription factor IIE subunit 1
  • InterPro Domains
    IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain
    IPR017919 Transcription factor TFE/TFIIEalpha HTH domain
    IPR021600 Transcription factor TFIIE alpha subunit, C-terminal
    IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR013137 Zinc finger, TFIIB-type
Molecular
Reagents
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  • All nucleic 62
    cDNA 60
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146403
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228779 Alpern D, et al., TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation. Elife. 2014;3:e03613

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory