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Gtf2e1 Gene Detail
Summary
  • Symbol
    Gtf2e1
  • Name
    general transcription factor II E, polypeptide 1 (alpha subunit)
  • Synonyms
    2610024P03Rik, 56kDa, FE, TFIIE-A
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921447
    NCBI Gene: 74197
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:37330158-37360151 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 26.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    635 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921447
 protein coding gene Chr16:37330152-37360151 (-)
129S1/SvImJ ENSMUSG00200027793
 protein coding gene Chr16:34266063-34296064 (-)
A/J ENSMUSG00195010583
 protein coding gene Chr16:33811398-33841409 (-)
AKR/J ENSMUSG00220026010
 protein coding gene Chr16:34188972-34218982 (-)
BALB/cJ ENSMUSG00180013072
 protein coding gene Chr16:34027038-34057047 (-)
C3H/HeJ ENSMUSG00175030658
 protein coding gene Chr16:34253767-34283567 (-)
C57BL/6NJ ENSMUSG00215017082
 protein coding gene Chr16:34101686-34131686 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020727
 protein coding gene Chr16:34571523-34602329 (-)
CAST/EiJ ENSTCUG00005029433
 protein coding gene Chr16:34547250-34577082 (-)
CBA/J ENSMUSG00210027141
 protein coding gene Chr16:34310842-34340640 (-)
DBA/2J ENSMUSG00185023507
 protein coding gene Chr16:34213871-34243669 (-)
FVB/NJ ENSMUSG00205021874
 protein coding gene Chr16:34187598-34217598 (-)
JF1/MsJ ENSUMUG00000022893
 protein coding gene Chr16:34426989-34457047 (-)
LP/J ENSMUSG00230031931
 protein coding gene Chr16:36786046-36815844 (-)
NOD/ShiLtJ ENSMUSG00190020915
 protein coding gene Chr16:34325766-34355772 (-)
NZO/HlLtJ ENSMUSG00225038114
 protein coding gene Chr16:39885379-39915177 (-)
PWK/PhJ ENSLUMG00010027761
 protein coding gene Chr16:34339772-34369692 (-)
SPRET/EiJ ENSMSPG00010015645
 protein coding gene Chr16:34325505-34353907 (-)
WSB/EiJ ENSIUOG00005023857
 protein coding gene Chr16:34399937-34429776 (-)



Homology
more
  • Human Ortholog
    GTF2E1, general transcription factor IIE subunit 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GTF2E1, general transcription factor IIE subunit 1
  • Synonyms
    FE, TF2E1, TFIIE-A
  • Links
    NCBI Gene ID: 2960
    UniProt: P29083

  • Chr Location
    3q13.33; chr3:120742370-120783368 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    723
  • Tissues
    117
  • cDNA Data
    60
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74197 NCBI Gene Model | MGI Sequence Detail 29994 C57BL/6J ±  kb
transcript NM_001355727 RefSeq | MGI Sequence Detail 3254 C57BL/6  
polypeptide Q9D0D5 UniProt | EBI | MGI Sequence Detail 440 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000008314 general transcription factor IIE subunit 1
    (term hierarchy)
  • InterPro Domains
    IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain
    IPR039997 Transcription factor E
    IPR017919 Transcription factor TFE/TFIIEalpha HTH domain
    IPR021600 Transcription factor TFIIE alpha subunit, C-terminal
    IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR013137 Zinc finger, TFIIB-type
Molecular
Reagents
less
  • All nucleic 63
    cDNA 61
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146403
References
more
  • Summaries
    All 45
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228779 Alpern D, et al., TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation. Elife. 2014;3:e03613
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory