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Gtf2e1 Gene Detail
Summary
  • Symbol
    Gtf2e1
  • Name
    general transcription factor II E, polypeptide 1 (alpha subunit)
  • Synonyms
    2610024P03Rik, 56kDa, FE, TFIIE-A
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921447
    NCBI Gene: 74197
  • Gene Overview
    MyGene.info: GTF2E1
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:37509795-37539773 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 26.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    179 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921447
protein coding gene Chr16:37509790-37539789 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022800
protein coding gene Chr16:35973689-36006118 (-)
A/J MGP_AJ_G0022765
protein coding gene Chr16:34183699-34214703 (-)
AKR/J MGP_AKRJ_G0022737
protein coding gene Chr16:35483381-35513557 (-)
BALB/cJ MGP_BALBcJ_G0022766
protein coding gene Chr16:34301425-34331420 (-)
C3H/HeJ MGP_C3HHeJ_G0022530
protein coding gene Chr16:35609962-35639597 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023213
protein coding gene Chr16:36820469-36850451 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020727
protein coding gene Chr16:34571523-34602329 (-)
CAST/EiJ MGP_CASTEiJ_G0022056
protein coding gene Chr16:35746279-35774701 (-)
CBA/J MGP_CBAJ_G0022501
protein coding gene Chr16:38416105-38450153 (-)
DBA/2J MGP_DBA2J_G0022633
protein coding gene Chr16:34083174-34112935 (-)
FVB/NJ MGP_FVBNJ_G0022608
protein coding gene Chr16:34108682-34138906 (-)
LP/J MGP_LPJ_G0022701
protein coding gene Chr16:35671498-35703544 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022627
protein coding gene Chr16:37563310-37593325 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023228
protein coding gene Chr16:35456187-35485807 (-)
PWK/PhJ MGP_PWKPhJ_G0021796
protein coding gene Chr16:34474049-34504192 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021627
protein coding gene Chr16:35356885-35386819 (-)
WSB/EiJ MGP_WSBEiJ_G0022100
protein coding gene Chr16:35530591-35560407 (-)



Homology
more
  • Human Ortholog
    GTF2E1, general transcription factor IIE subunit 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GTF2E1, general transcription factor IIE subunit 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FE, TF2E1, TFIIE-A
  • Links
    NCBI Gene ID: 2960
    neXtProt AC: NX_P29083
    UniProt: P29083

  • Chr Location
    3q13.33; chr3:120742711-120783134 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 38062
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GTF2E1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 74197 NCBI Gene Model | MGI Sequence Detail 29979 C57BL/6J ±  kb
transcript NM_001355727 RefSeq | MGI Sequence Detail 3254 C57BL/6  
polypeptide Q9D0D5 UniProt | EBI | MGI Sequence Detail 440 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000008314 general transcription factor IIE subunit 1
  • InterPro Domains
    IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain
    IPR017919 Transcription factor TFE/TFIIEalpha HTH domain
    IPR021600 Transcription factor TFIIE alpha subunit, C-terminal
    IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR013137 Zinc finger, TFIIB-type
Molecular
Reagents
less
  • All nucleic 63
    cDNA 61
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146403
References
more
  • Summaries
    All 42
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228779 Alpern D, et al., TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation. Elife. 2014;3:e03613

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory