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Rnd3
Gene Detail
Symbol

Name
ID
Rnd3
Rho family GTPase 3
MGI:1921444
Synonyms
2610017M01Rik, Arhe, Rhoe
Feature Type
protein coding gene
Genetic Map
Chromosome 2
29.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:51130438-51149111 bp, - strand
From VEGA annotation of GRCm38

  18674 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21074  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: small GTPase, Rho type
Gene Tree: Rnd3

Human
homologs
Human Homolog RND3, Rho family GTPase 3
NCBI Gene ID 390
neXtProt AC  NX_P61587
Human Synonyms  ARHE, memB, Rho8, RhoE
Human Chr (Location)  2q23.3; chr2:150468193-150487695 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(9) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a mutation in this gene display premature death with postnatal growth retardation and wasting, delayed development, absence of the common peroneal nerve and impaired motor capabilities.
 
Interactions
Rnd3 interacts with 268 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process small GTPase mediated signal transduction
Component extracellular vesicular exosome, focal adhesion, ...
Function GTP binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (45)    Tissues (31)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 45
cDNA source data(9)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000012429 (Evidence)
Ensembl Gene ModelENSMUSG00000017144 (Evidence)
Entrez Gene74194 (Evidence)
DFCITC1575622, TC1624021
DoTSDT.101277384, DT.530332
NIA Mouse Gene IndexU022610
PDB1GWN
Consensus CDS ProjectCCDS16028.1
International Mouse Knockout Project StatusRnd3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012429 VEGA Gene Model | MGI Sequence Detail 18674 C57BL/6J ±  kb
transcript OTTMUST00000029556 VEGA | MGI Sequence Detail 2828 Not Applicable 
polypeptide OTTMUSP00000013299 VEGA | MGI Sequence Detail 244 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(227 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003578 Small GTPase superfamily, Rho type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000014063 rho-related GTP-binding protein RhoE
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:207259 Pacary E, et al., Rnd3 coordinates early steps of cortical neurogenesis through actin-dependent and -independent mechanisms. Nat Commun. 2013;4:1635
All references(47)
Other
accession IDs
MGI:2139033

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory