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Tgm5
Gene Detail
 Symbol
Name
ID
Tgm5
transglutaminase 5
MGI:1921426
Synonyms 2310007C07Rik, TGx
Feature Type protein coding gene
Genetic Map
Chromosome 2
60.37 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:121046111-121085841 bp, - strand
From VEGA annotation of GRCm38

  39731 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20899  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

Protein SuperFamily: TGM_EBP42
Gene Tree: Tgm5

Human
homologs
Human Homolog TGM5, transglutaminase 5
NCBI Gene ID 9333
neXtProt AC  NX_O43548
Human Synonyms  TGASE5, TGASEX, TGM6, TGMX, TGX
Human Chr (Location)  15q15.2; chr15:43232595-43266857 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human TGM5
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tgm5 interacts with 62 markers (Mir18b, Mir23a, Mir29b-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process peptide cross-linking
Component cytoplasm
Function metal ion binding, protein-glutamine gamma-glutamyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (173)    Tissues (164)    Images (9)
Theiler Stages: 17, 21, 22, 23
Assay TypeResults
RNA in situ 173
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(9) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000015969 (Evidence)
Ensembl Gene ModelENSMUSG00000053675 (Evidence)
Entrez Gene74176 (Evidence)
UniGene20187
DFCITC1589287, TC1744245
DoTSDT.91401542
NIA Mouse Gene IndexU096801
EC2.3.2.13
Consensus CDS ProjectCCDS16632.1
International Mouse Knockout Project StatusTgm5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015969 VEGA Gene Model | MGI Sequence Detail 39731 C57BL/6J ±  kb
transcript OTTMUST00000037997 VEGA | MGI Sequence Detail 2613 Not Applicable 
polypeptide OTTMUSP00000017043 VEGA | MGI Sequence Detail 724 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(475 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR023608 Protein-glutamine gamma-glutamyltransferase, eukaryota
InterPro IPR013808 Transglutaminase, conserved site
InterPro IPR008958 Transglutaminase, C-terminal
InterPro IPR002931 Transglutaminase-like
InterPro IPR001102 Transglutaminase, N-terminal
Protein Ontology PR:000016296 protein-glutamine gamma-glutamyltransferase 5
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory