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Tgm5
Gene Detail
Symbol

Name
ID
Tgm5
transglutaminase 5
MGI:1921426
Synonyms
2310007C07Rik, TGx
Feature Type
protein coding gene
Genetic Map
Chromosome 2
60.37 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:121046111-121085841 bp, - strand
From VEGA annotation of GRCm38

  39731 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20899  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

HCOP human homology predictions: TGM5
Protein SuperFamily: TGM_EBP42
Gene Tree: Tgm5

Human
homologs
TGM5, transglutaminase 5
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9333
neXtProt AC: NX_O43548

Human Synonyms: PSS2, TGASE5, TGASEX, TGM6, TGMX, TGX

Human Chr (Location): 15q15.2; chr15:43232595-43267023 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human TGM5

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tgm5 interacts with 61 markers (Mir18b, Mir23a, Mir29b-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process peptide cross-linking
Component cytoplasm
Function metal ion binding, protein-glutamine gamma-glutamyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (173)    Tissues (164)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 173
cDNA source data(8)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100486682    NEW 
Molecular
reagents
All nucleic(10) cDNA(9) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000015969 (Evidence)
Ensembl Gene Model ENSMUSG00000053675 (Evidence)
Entrez Gene 74176 (Evidence)
UniGene 20187
DFCI TC1589287, TC1744245
DoTS DT.91401542
NIA Mouse Gene Index U096801
EC 2.3.2.13
Consensus CDS Project CCDS16632.1
International Mouse Phenotyping Consortium Status Tgm5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015969 VEGA Gene Model | MGI Sequence Detail 39731 C57BL/6J ±  kb
transcript OTTMUST00000037997 VEGA | MGI Sequence Detail 2613 Not Applicable 
polypeptide OTTMUSP00000017043 VEGA | MGI Sequence Detail 724 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(475 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR023608 Protein-glutamine gamma-glutamyltransferase, eukaryota
InterPro IPR013808 Transglutaminase, conserved site
InterPro IPR008958 Transglutaminase, C-terminal
InterPro IPR002931 Transglutaminase-like
InterPro IPR001102 Transglutaminase, N-terminal
Protein Ontology PR:000016296 protein-glutamine gamma-glutamyltransferase 5
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory