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Gtsf1
Gene Detail
Symbol

Name
ID
Gtsf1
gametocyte specific factor 1
MGI:1921424
Synonyms
1700006H03Rik, Cue110
Feature Type
protein coding gene
Genetic Map
Chromosome 15
58.93 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:103402405-103430470 bp, - strand
From VEGA annotation of GRCm38

  28066 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16942  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Gtsf1

Human
homologs
Human Homolog GTSF1, gametocyte specific factor 1
NCBI Gene ID 121355
neXtProt AC  NX_Q8WW33
Human Synonyms  FAM112B
Human Chr (Location)  12q13.13; chr12:54455952-54473602 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(17) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit male infertility due to arrested male meiosis and apoptosis of male germ cells.
 
Interactions
Gtsf1 interacts with 35 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Component cytoplasm
Function metal ion binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (114)    Tissues (50)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 22
RNA in situ 16
Western blot 12
RT-PCR 64
cDNA source data(37)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(41) cDNA(37) Primer pair(3) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000034009 (Evidence)
Ensembl Gene ModelENSMUSG00000022487 (Evidence)
Entrez Gene74174 (Evidence)
UniGene325325
DFCITC1582665
DoTSDT.103568390, DT.55245272, DT.55223902
NIA Mouse Gene IndexU036714
Consensus CDS ProjectCCDS49744.1
International Mouse Knockout Project StatusGtsf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034009 VEGA Gene Model | MGI Sequence Detail 28066 C57BL/6J ±  kb
transcript OTTMUST00000085861 VEGA | MGI Sequence Detail 698 Not Applicable 
polypeptide OTTMUSP00000046432 VEGA | MGI Sequence Detail 194 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(11) UniProt(9)
Polymorphisms
SNPs within 2kb(63 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022776 TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain
InterPro IPR007917 Uncharacterised protein family UPF0224
Protein Ontology PR:000008341 gametocyte-specific factor 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory