Acbd5 MGI Mouse Gene Detail - MGI:1921409 - acyl-Coenzyme A binding domain containing 5

Symbol

Acbd5
Name

acyl-Coenzyme A binding domain containing 5
Synonyms

1300014E15Rik

Feature Type

protein coding gene
IDs

MGI:1921409
NCBI Gene: 74159
Alliance

gene page
Transcription Start Sites

10 TSS

Sequence Map

Chr2:23068166-23114513 bp, + strand
From NCBI annotation of GRCm38

View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 15.21 cM, cytoband A3
Mapping Data

2 experiments

SNPs within 2kb

78 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1921409	protein coding gene	Chr2:23068166-23115558 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0025395	protein coding gene	Chr2:20814527-20859894 (+)
A/J	MGP_AJ_G0025373	protein coding gene	Chr2:19972151-20017425 (+)
AKR/J	MGP_AKRJ_G0025342	protein coding gene	Chr2:20682233-20728924 (+)
BALB/cJ	MGP_BALBcJ_G0025368	protein coding gene	Chr2:20076976-20123222 (+)
C3H/HeJ	MGP_C3HHeJ_G0025129	protein coding gene	Chr2:20602565-20645305 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025812	protein coding gene	Chr2:21408495-21451419 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0023226	protein coding gene	Chr2:19052226-19101123 (+)
CAST/EiJ	MGP_CASTEiJ_G0024592	protein coding gene	Chr2:20517598-20561596 (+)
CBA/J	MGP_CBAJ_G0025107	protein coding gene	Chr2:22228792-22283245 (+)
DBA/2J	MGP_DBA2J_G0025240	protein coding gene	Chr2:19859145-19906264 (+)
FVB/NJ	MGP_FVBNJ_G0025202	protein coding gene	Chr2:19643662-19688173 (+)
LP/J	MGP_LPJ_G0025326	protein coding gene	Chr2:20739753-20785250 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0025233	protein coding gene	Chr2:22292470-22342569 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025871	protein coding gene	Chr2:20576510-20613961 (+)
PWK/PhJ	MGP_PWKPhJ_G0024341	protein coding gene	Chr2:19690227-19737876 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0024141	protein coding gene	Chr2:20681580-20732840 (+)
WSB/EiJ	MGP_WSBEiJ_G0024662	protein coding gene	Chr2:20711118-20756517 (+)

Human Ortholog

ACBD5, acyl-CoA binding domain containing 5

Vertebrate Orthologs

12

Human Ortholog

ACBD5, acyl-CoA binding domain containing 5
Orthology source: HomoloGene, HGNC
Links

HGNC:23338

NCBI Gene ID: 91452

neXtProt AC: NX_Q5T8D3

UniProt: Q5T8D3
Chr Location

10p12.1; chr10:27182624-27248674 (-) GRCh38.p7

HomoloGene

Vertebrate Homology Class 12541
1 human;1 mouse;3 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
HCOP

human homology predictions: ACBD5
Protein SuperFamily

membrane-associated diazepam binding inhibitor
Gene Tree

Acbd5

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Phenotype Summary

20 phenotypes from 1 allele in 1 genetic background
8 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

14
Gene trapped

11
Targeted

3
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

21 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

8
GO References

3

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell death	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	nucleic acid-templated transcription	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

712
Tissues

11
cDNA Data

9
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase acbd5

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Acbd5 interacts with 313 markers (Mir7-1, Mir15a, Mir16-1, ...) View All

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All Sequences

103
RefSeq

29
UniProt

8
CCDS

CCDS50514.1, CCDS50515.1, CCDS50516.1, CCDS57156.1, CCDS89434.1, CCDS89435.1, CCDS89437.1

Ensembl

ENSMUSG00000026781 (Evidence)
NCBI Gene

74159

			Length	Strain/Species	Flank
genomic	74159	NCBI Gene Model \| MGI Sequence Detail	46348	C57BL/6J	± kb
transcript	NM_001355637	RefSeq \| MGI Sequence Detail	3757	C57BL/6
polypeptide	Q5XG73	UniProt \| EBI \| MGI Sequence Detail	508	Not Applicable

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UniProt

8 Sequences
Protein Ontology

PR:000032706 acyl-CoA-binding domain-containing protein 5

(term hierarchy)
InterPro Domains

IPR016347 Acyl-CoA-binding domain-containing protein 5

IPR000582 Acyl-CoA-binding protein, ACBP

IPR022408 Acyl-CoA-binding protein, ACBP, conserved site

IPR035984 Acyl-CoA binding protein superfamily

IPR014352 FERM/acyl-CoA-binding protein superfamily

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All nucleic 10

cDNA 9

Primer pair 1

Microarray probesets 4

Summaries

All 32

Developmental Gene Expression 2

Gene Ontology 3

Phenotypes 8
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:246912 Ye A, et al., PEG3 control on the mammalian MSL complex. PLoS One. 2017;12(6):e0178363

TSS for Acbd5:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr16529	Chr2:23068217-23068241 (+)	63 bp
Tssr16530	Chr2:23068261-23068284 (+)	107 bp
Tssr16531	Chr2:23069057-23069089 (+)	907 bp
Tssr16532	Chr2:23069117-23069144 (+)	965 bp
Tssr16533	Chr2:23069149-23069169 (+)	993 bp
Tssr16534	Chr2:23069188-23069208 (+)	1,032 bp
Tssr16535	Chr2:23069210-23069252 (+)	1,065 bp
Tssr16536	Chr2:23069413-23069424 (+)	1,253 bp
Tssr16537	Chr2:23069441-23069455 (+)	1,282 bp
Tssr16538	Chr2:23098089-23098093 (+)	29,925 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 03/24/2020 MGI 6.15