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Unkl Gene Detail
Summary
  • Symbol
    Unkl
  • Name
    unkempt family like zinc finger
  • Synonyms
    1300004G08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921404
    NCBI Gene: 74154
  • Gene Overview
    MyGene.info: UNKL
Location & Maps
more
  • Sequence Map
    Chr17:25188397-25234443 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      46047 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 12.53 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    UNKL, unkempt family like zinc finger
  • Vertebrate Orthologs
    9
  • Human Ortholog
    UNKL, unkempt family like zinc finger
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C16orf28, ZC3H5L, ZC3HDC5L
  • Links
    NCBI Gene ID: 64718
    neXtProt AC: NX_Q9H9P5

  • Chr Location
    16p13.3; chr16:1363205-1414749 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 62673
    1 human;1 mouse;1 rat;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: UNKL
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    15
  • Gene trapped
    11
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    2 involving Unkl
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035060 VEGA Gene Model | MGI Sequence Detail 46047 C57BL/6J ±  kb
transcript OTTMUST00000089175 VEGA | MGI Sequence Detail 4779 Not Applicable  
polypeptide OTTMUSP00000048699 VEGA | MGI Sequence Detail 727 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    392 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 4
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228778 Avet-Rochex A, et al., Unkempt is negatively regulated by mTOR and uncouples neuronal differentiation from growth control. PLoS Genet. 2014 Sep;10(9):e1004624

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support.
last database update
11/29/2016
MGI 6.06
The Jackson Laboratory