About   Help   FAQ
Unkl Gene Detail
Summary
  • Symbol
    Unkl
  • Name
    unkempt family like zinc finger
  • Synonyms
    1300004G08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921404
    NCBI Gene: 74154
  • Gene Overview
    MyGene.info: UNKL
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:25188397-25234443 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 12.53 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    392 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921404
protein coding gene Chr17:25188350-25234443 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023343
protein coding gene Chr17:24231894-24284451 (+)
A/J MGP_AJ_G0023302
protein coding gene Chr17:23557181-23606105 (+)
AKR/J MGP_AKRJ_G0023268
protein coding gene Chr17:23647210-23695805 (+)
BALB/cJ MGP_BALBcJ_G0023307
protein coding gene Chr17:23753890-23802820 (+)
C3H/HeJ MGP_C3HHeJ_G0023067
protein coding gene Chr17:24024557-24072401 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023750
protein coding gene Chr17:25295418-25345810 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021225
protein coding gene Chr17:21020353-21067418 (+)
CAST/EiJ MGP_CASTEiJ_G0022569
protein coding gene Chr17:23870544-23921254 (+)
CBA/J MGP_CBAJ_G0023042
protein coding gene Chr17:26156357-26211352 (+)
DBA/2J MGP_DBA2J_G0023172
protein coding gene Chr17:23144860-23191523 (+)
FVB/NJ MGP_FVBNJ_G0023142
protein coding gene Chr17:22870486-22920059 (+)
LP/J MGP_LPJ_G0023249
protein coding gene Chr17:24525005-24577718 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023161
protein coding gene Chr17:25818823-25872385 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023789
protein coding gene Chr17:23930646-23983567 (+)
PWK/PhJ MGP_PWKPhJ_G0022318
protein coding gene Chr17:21907029-21954308 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022136
protein coding gene Chr17:22003069-22052572 (+)
WSB/EiJ MGP_WSBEiJ_G0022632
protein coding gene Chr17:24002362-24057827 (+)



Homology
more
  • Human Ortholog
    UNKL, unkempt family like zinc finger
  • Vertebrate Orthologs
    9
  • Human Ortholog
    UNKL, unkempt family like zinc finger
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C16orf28, ZC3H5L, ZC3HDC5L
  • Links
    NCBI Gene ID: 64718
    neXtProt AC: NX_Q9H9P5
    UniProt: Q9H9P5

  • Chr Location
    16p13.3; chr16:1363205-1414749 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 62673
    1 human;1 mouse;1 rat;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: UNKL
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015127 Ensembl Gene Model | MGI Sequence Detail 46047 C57BL/6J ±  kb
transcript ENSMUST00000039734 Ensembl | MGI Sequence Detail 4779 Not Applicable  
polypeptide ENSMUSP00000039670 Ensembl | MGI Sequence Detail 727 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228778 Avet-Rochex A, et al., Unkempt is negatively regulated by mTOR and uncouples neuronal differentiation from growth control. PLoS Genet. 2014 Sep;10(9):e1004624

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory