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Cyp2s1 Gene Detail
Summary
  • Symbol
    Cyp2s1
  • Name
    cytochrome P450, family 2, subfamily s, polypeptide 1
  • Synonyms
    1200011C15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921384
    NCBI Gene: 74134
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:25501894-25515950 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 14.05 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    441 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921384
 protein coding gene Chr7:25501894-25516338 (-)
129S1/SvImJ ENSMUSG00200041894
 protein coding gene Chr7:15499039-15513474 (-)
A/J ENSMUSG00195052783
 protein coding gene Chr7:17942953-17957400 (-)
AKR/J ENSMUSG00220046025
 protein coding gene Chr7:26433184-26447623 (+)
BALB/cJ ENSMUSG00180053049
 protein coding gene Chr7:16014915-16029360 (-)
C3H/HeJ ENSMUSG00175046426
 protein coding gene Chr7:17058966-17073405 (-)
C57BL/6NJ ENSMUSG00215054781
 protein coding gene Chr7:15418857-15433298 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029383
 protein coding gene Chr7:25019332-25032016 (-)
CAST/EiJ ENSTCUG00005051068
 protein coding gene Chr7:17110956-17125268 (-)
CBA/J ENSMUSG00210051944
 protein coding gene Chr7:16244660-16259100 (-)
DBA/2J ENSMUSG00185054414
 protein coding gene Chr7:19458455-19472893 (-)
FVB/NJ ENSMUSG00205050956
 protein coding gene Chr7:16255360-16269803 (-)
JF1/MsJ ENSUMUG00000031878
 protein coding gene Chr7:23741583-23756298 (-)
LP/J ENSMUSG00230051842
 protein coding gene Chr7:24725157-24739586 (-)
NOD/ShiLtJ ENSMUSG00190044960
 protein coding gene Chr7:15718679-15733128 (-)
NZO/HlLtJ ENSMUSG00225023842
 protein coding gene Chr7:23400426-23414867 (-)
PWK/PhJ ENSLUMG00010048435
 protein coding gene Chr7:15675164-15689297 (-)
SPRET/EiJ ENSMSPG00010049783
 protein coding gene Chr7:15347593-15362605 (-)
WSB/EiJ ENSIUOG00005052534
 protein coding gene Chr7:10214249-10228697 (-)



Homology
more
  • Human Ortholog
    CYP2S1, cytochrome P450 family 2 subfamily S member 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2S1, cytochrome P450 family 2 subfamily S member 1
  • Synonyms
    CYPIIS1
  • Links
    NCBI Gene ID: 29785
    UniProt: Q96SQ9

  • Chr Location
    19q13.2; chr19:41193045-41207540 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Mice homozygous for a knock-out allele are viable and fertile and appear normal in terms of body weight, growth rate, organ weight, and daily activity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    38
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    648
  • Tissues
    14
  • cDNA Data
    64
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 74134 NCBI Gene Model | MGI Sequence Detail 14057 C57BL/6J ±  kb
transcript NM_028775 RefSeq | MGI Sequence Detail 2623 C57BL/6  
polypeptide Q9DBX6 UniProt | EBI | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 65
    cDNA 64
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2142151, MGI:2142335
References
more
  • Summaries
    All 48
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:386971 Tran LM, et al., Role of P450 enzymes of the Cyp2abfgs gene subfamilies in tobacco smoke-induced lung tumorigenesis in mice. Carcinogenesis. 2026 Mar 19;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory