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Cyp2s1
Gene Detail
 Symbol
Name
ID
Cyp2s1
cytochrome P450, family 2, subfamily s, polypeptide 1
MGI:1921384
Synonyms 1200011C15Rik
Feature Type protein coding gene
Genetic Map
Chromosome 7
14.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:25802475-25816913 bp, - strand
From VEGA annotation of GRCm38

  14439 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75274  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2s1

Human
homologs
Human Homolog CYP2S1, cytochrome P450, family 2, subfamily S, polypeptide 1
NCBI Gene ID 29785
neXtProt AC  NX_Q96SQ9
Human Chr (Location)  19q13.1; chr19:41193210-41207539 (+)  GRCh38
Alleles
and
phenotypes
All alleles(4) : Targeted(4)
 
Mice homozygous for a knock-out allele are viable and fertile and appear normal in terms of body weight, growth rate, organ weight, and daily activity.
 
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process oxidation-reduction process
Component endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function aromatase activity, heme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (51)    Tissues (14)    Images (11)
Theiler Stages: 10, 18, 23, 25, 28
Assay TypeResults
RNA in situ 15
RT-PCR 36
cDNA source data(63)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(64) cDNA(63) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000024365 (Evidence)
Ensembl Gene ModelENSMUSG00000040703 (Evidence)
Entrez Gene74134 (Evidence)
UniGene275188
DFCITC1577039
DoTSDT.101249619, DT.491471, DT.97347925
NIA Mouse Gene IndexU028285
EC1.14.14.1
Consensus CDS ProjectCCDS20997.1
International Mouse Knockout Project StatusCyp2s1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024365 VEGA Gene Model | MGI Sequence Detail 14439 C57BL/6J ±  kb
transcript OTTMUST00000059692 VEGA | MGI Sequence Detail 2745 Not Applicable 
polypeptide OTTMUSP00000029055 VEGA | MGI Sequence Detail 501 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(2) UniProt(4)
Polymorphisms SNPs within 2kb(49 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR002401 Cytochrome P450, E-class, group I
InterPro IPR008067 Cytochrome P450, E-class, group I, CYP2A-like
Protein Ontology PR:000006126 cytochrome P450 2S1
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:190445 Wei Y, et al., Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model. Drug Metab Dispos. 2013 Jan;41(1):132-40
All references(37)
Other
accession IDs
MGI:2142151, MGI:2142335

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory