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Cyp2s1 Gene Detail
Summary
  • Symbol
    Cyp2s1
  • Name
    cytochrome P450, family 2, subfamily s, polypeptide 1
  • Synonyms
    1200011C15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921384
    NCBI Gene: 74134
  • Gene Overview
    MyGene.info: CYP2S1
Location & Maps
more
  • Sequence Map
    Chr7:25802475-25816913 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14439 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CYP2S1, cytochrome P450 family 2 subfamily S member 1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    CYP2S1, cytochrome P450 family 2 subfamily S member 1
    Orthology source: HomoloGene
  • Synonyms
    CYPIIS1
  • Links
    NCBI Gene ID: 29785
    neXtProt AC: NX_Q96SQ9

  • Chr Location
    19q13.1; chr19:41193207-41207539 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
  • All Mutations and Alleles
    6
  • Targeted
    6
  • Genomic Mutations
    2 involving Cyp2s1
  • Incidental Mutations
Mice homozygous for a knock-out allele are viable and fertile and appear normal in terms of body weight, growth rate, organ weight, and daily activity.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024365 VEGA Gene Model | MGI Sequence Detail 14439 C57BL/6J ±  kb
transcript OTTMUST00000059692 VEGA | MGI Sequence Detail 2745 Not Applicable  
polypeptide OTTMUSP00000029055 VEGA | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    49 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 64
    cDNA 63
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGI:2142151, MGI:2142335
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:216691 Li L, et al., Identification of cytochrome P450 enzymes critical for lung tumorigenesis by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): insights from a novel Cyp2abfgs-null mouse. Carcinogenesis. 2014 Nov;35(11):2584-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory