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Cyp2s1 Gene Detail
Summary
  • Symbol
    Cyp2s1
  • Name
    cytochrome P450, family 2, subfamily s, polypeptide 1
  • Synonyms
    1200011C15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921384
    NCBI Gene: 74134
  • Gene Overview
    MyGene.info: CYP2S1
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:25802476-25816530 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 14.05 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    48 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921384
protein coding gene Chr7:25802475-25816913 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031880
protein coding gene Chr7:24319777-24334265 (-)
A/J MGP_AJ_G0031859
protein coding gene Chr7:23681346-23696825 (-)
AKR/J MGP_AKRJ_G0031788
protein coding gene Chr7:24294776-24309894 (-)
BALB/cJ MGP_BALBcJ_G0031864
protein coding gene Chr7:23917319-23932752 (-)
C3H/HeJ MGP_C3HHeJ_G0031585
protein coding gene Chr7:24703265-24717669 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032328
protein coding gene Chr7:25131177-25148273 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029383
protein coding gene Chr7:25019332-25032016 (-)
CAST/EiJ MGP_CASTEiJ_G0030925
protein coding gene Chr7:18108739-18124110 (-)
CBA/J MGP_CBAJ_G0031550
protein coding gene Chr7:26023557-26040484 (-)
DBA/2J MGP_DBA2J_G0031704
protein coding gene Chr7:23573140-23587415 (-)
FVB/NJ MGP_FVBNJ_G0031657
protein coding gene Chr7:23604742-23618974 (-)
LP/J MGP_LPJ_G0031783
protein coding gene Chr7:24592635-24609243 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031694
protein coding gene Chr7:25739647-25755023 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032360
protein coding gene Chr7:23930503-23947220 (-)
PWK/PhJ MGP_PWKPhJ_G0030649
protein coding gene Chr7:18533972-18548830 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030479
protein coding gene Chr7:15253213-15270218 (-)
WSB/EiJ MGP_WSBEiJ_G0031028
protein coding gene Chr7:24151160-24166883 (-)



Homology
more
  • Human Ortholog
    CYP2S1, cytochrome P450 family 2 subfamily S member 1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    CYP2S1, cytochrome P450 family 2 subfamily S member 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CYPIIS1
  • Links
    NCBI Gene ID: 29785
    neXtProt AC: NX_Q96SQ9
    UniProt: Q96SQ9

  • Chr Location
    19q13.2; chr19:41193207-41207539 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Mice homozygous for a knock-out allele are viable and fertile and appear normal in terms of body weight, growth rate, organ weight, and daily activity.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 74134 NCBI Gene Model | MGI Sequence Detail 14055 C57BL/6J ±  kb
transcript NM_028775 RefSeq | MGI Sequence Detail 2623 C57BL/6  
polypeptide Q9DBX6 UniProt | EBI | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 65
    cDNA 64
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2142151, MGI:2142335
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:216691 Li L, et al., Identification of cytochrome P450 enzymes critical for lung tumorigenesis by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): insights from a novel Cyp2abfgs-null mouse. Carcinogenesis. 2014 Nov;35(11):2584-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory