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Dmgdh
Gene Detail
Symbol

Name
ID
Dmgdh
dimethylglycine dehydrogenase precursor
MGI:1921379
Synonyms
1200014D15Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 13
47.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:93674433-93752831 bp, + strand
From VEGA annotation of GRCm38

  78399 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8372  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: dimethylglycine dehydrogenase
Gene Tree: Dmgdh

Human
homologs
Human Homolog DMGDH, dimethylglycine dehydrogenase
NCBI Gene ID 29958
neXtProt AC  NX_Q9UI17
Human Synonyms  DMGDHD, ME2GLYDH
Human Chr (Location)  5q14.1; chr5:78997564-79069674 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human DMGDH
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Dmgdh interacts with 76 markers (Mir10a, Mir10b, Mir15b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (110)    Tissues (108)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 110
cDNA source data(26)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(26) cDNA(26)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000024424 (Evidence)
Ensembl Gene ModelENSMUSG00000042102 (Evidence)
Entrez Gene74129 (Evidence)
UniGene21789
DFCITC1582629
DoTSDT.50316269
NIA Mouse Gene IndexU015122
EC1.5.8.4
Consensus CDS ProjectCCDS26690.1
International Mouse Knockout Project StatusDmgdh
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024424 VEGA Gene Model | MGI Sequence Detail 78399 C57BL/6J ±  kb
transcript OTTMUST00000059874 VEGA | MGI Sequence Detail 2990 Not Applicable 
polypeptide OTTMUSP00000029163 VEGA | MGI Sequence Detail 869 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(869 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006076 FAD dependent oxidoreductase
InterPro IPR013977 Glycine cleavage T-protein, C-terminal barrel
InterPro IPR006222 Glycine cleavage T-protein, N-terminal
InterPro IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1
Protein Ontology PR:000006538 dimethylglycine dehydrogenase, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)
Other
accession IDs
MGI:2145286

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory