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Rbm19 Gene Detail
Summary
  • Symbol
    Rbm19
  • Name
    RNA binding motif protein 19
  • Synonyms
    1200009A02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921361
    NCBI Gene: 74111
  • Gene Overview
    MyGene.info: RBM19
Location & Maps
more
  • Sequence Map
    Chr5:120116465-120198981 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      82517 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 60.58 cM, cytoband F
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RBM19, RNA binding motif protein 19
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RBM19, RNA binding motif protein 19
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 9904
    neXtProt AC: NX_Q9Y4C8

  • Chr Location
    12q24.21; chr12:113816738-113966371 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 7158
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: RBM19
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    16
  • Chemically induced (other)
    1
  • Gene trapped
    12
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Rbm19
  • Incidental Mutations
Mice homozygous for a gene trap allele exhibit failure to undergo compaction, growth arrest at the morula stage, and apoptosis such that no embryos are observed at E6.5.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000056239 VEGA Gene Model | MGI Sequence Detail 82517 C57BL/6J ±  kb
transcript OTTMUST00000138987 VEGA | MGI Sequence Detail 4010 Not Applicable  
polypeptide OTTMUSP00000072983 VEGA | MGI Sequence Detail 952 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    22 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 56
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141122
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:185368 Smemo S, et al., Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease. Hum Mol Genet. 2012 Jul 15;21(14):3255-63

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory