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Them7 Gene Detail
Summary
  • Symbol
    Them7
  • Name
    thioesterase superfamily member 7
  • Synonyms
    0610012H03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921338
    NCBI Gene: 74088
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:105224320-105379796 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 55.09 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1318 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921338
protein coding gene Chr2:105224255-105379860 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026228
protein coding gene Chr2:107376834-107538887 (+)
A/J MGP_AJ_G0026189
protein coding gene Chr2:102895099-103055393 (+)
AKR/J MGP_AKRJ_G0026169
protein coding gene Chr2:105703945-105865291 (+)
BALB/cJ MGP_BALBcJ_G0026198
protein coding gene Chr2:103175505-103331618 (+)
C3H/HeJ MGP_C3HHeJ_G0025948
protein coding gene Chr2:106022506-106175624 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026649
protein coding gene Chr2:110913844-111067999 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024035
protein coding gene Chr2:98693174-98849252 (+)
CAST/EiJ MGP_CASTEiJ_G0025413
protein coding gene Chr2:106538388-106702228 (+)
CBA/J MGP_CBAJ_G0025926
protein coding gene Chr2:114723627-114895848 (+)
DBA/2J MGP_DBA2J_G0026064
protein coding gene Chr2:102437056-102595394 (+)
FVB/NJ MGP_FVBNJ_G0026027
protein coding gene Chr2:101420822-101577243 (+)
LP/J MGP_LPJ_G0026167
protein coding gene Chr2:107492849-107660812 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026051
protein coding gene Chr2:118575608-118737915 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026703
protein coding gene Chr2:105894072-106056161 (+)
PWK/PhJ MGP_PWKPhJ_G0025148
protein coding gene Chr2:101980067-102136717 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024948
protein coding gene Chr2:105117832-105287263 (+)
WSB/EiJ MGP_WSBEiJ_G0025480
protein coding gene Chr2:106633021-106798258 (+)



Homology
more
  • Human Ortholog
    THEM7P, thioesterase superfamily member 7, pseudogene
  • Vertebrate Orthologs
    4
  • Human Ortholog
    THEM7P, thioesterase superfamily member 7, pseudogene
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 106480297

  • Chr Location
    11p13; chr11:32112049-32168823 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000055312 Ensembl Gene Model | MGI Sequence Detail 155477 C57BL/6J ±  kb
transcript ENSMUST00000068813 Ensembl | MGI Sequence Detail 1556 Not Applicable  
polypeptide ENSMUSP00000063340 Ensembl | MGI Sequence Detail 223 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR029069 HotDog domain superfamily
    IPR006683 Thioesterase domain
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory