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Slc7a13 Gene Detail
Summary
  • Symbol
    Slc7a13
  • Name
    solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
  • Synonyms
    0610009O04Rik, AGT1, AGT-1, XAT2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921337
    NCBI Gene: 74087
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:19818727-19842213 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 7.63 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    86 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921337
protein coding gene Chr4:19818725-19842218 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028084
protein coding gene Chr4:16822555-16844167 (+)
A/J MGP_AJ_G0028042
protein coding gene Chr4:16361332-16393098 (+)
AKR/J MGP_AKRJ_G0028007
protein coding gene Chr4:16724233-16748729 (+)
BALB/cJ MGP_BALBcJ_G0028053
protein coding gene Chr4:16341270-16368139 (+)
C3H/HeJ MGP_C3HHeJ_G0027783
protein coding gene Chr4:16822275-16853805 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028496
protein coding gene Chr4:17507540-17534830 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025838
protein coding gene Chr4:15143913-15168764 (+)
CAST/EiJ MGP_CASTEiJ_G0027238
protein coding gene Chr4:16646712-16671335 (+)
CBA/J MGP_CBAJ_G0027756
protein coding gene Chr4:18012272-18043787 (+)
DBA/2J MGP_DBA2J_G0027899
protein coding gene Chr4:16184285-16205716 (+)
FVB/NJ MGP_FVBNJ_G0027865
protein coding gene Chr4:15903473-15928999 (+)
LP/J MGP_LPJ_G0028008
protein coding gene Chr4:16879992-16902855 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027898
protein coding gene Chr4:19067803-19101000 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028555
protein coding gene Chr4:16622135-16644764 (+)
PWK/PhJ MGP_PWKPhJ_G0026958
protein coding gene Chr4:16078365-16103412 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026787
protein coding gene Chr4:16471792-16501634 (+)
WSB/EiJ MGP_WSBEiJ_G0027315
protein coding gene Chr4:16664200-16689931 (+)



Homology
more
  • Human Ortholog
    SLC7A13, solute carrier family 7 member 13
  • Vertebrate Orthologs
    6
  • Human Ortholog
    SLC7A13, solute carrier family 7 member 13
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AGT1, AGT-1, XAT2
  • Links
    NCBI Gene ID: 157724
    neXtProt AC: NX_Q8TCU3
    UniProt: Q8TCU3

  • Chr Location
    8q21.3; chr8:86213909-86230380 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74087 NCBI Gene Model | MGI Sequence Detail 23487 C57BL/6J ±  kb
    transcript NM_028746 RefSeq | MGI Sequence Detail 2134 C57BL/6  
    polypeptide Q91WN3 UniProt | EBI | MGI Sequence Detail 478 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 40
      cDNA 40

      Microarray probesets 3
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:236757 West DB, et al., Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. PLoS Genet. 2016 Feb;12(2):e1005691

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/08/2019
    MGI 6.14
    The Jackson Laboratory